BETAGAN Dosage & Rx Info | Uses, Side Effects

Betagan Generic Name & Formulations

Legal Class

General Description

Levobunolol HCl 0.5%; oph. soln; contains benzalkonium chloride, sodium metabisulfite.

Pharmacological Class

Noncardioselective beta-blocker.

How Supplied

Soln—5mL, 10mL, 15mL

Manufacturer

AbbVie

Generic Availability

YES

Betagan Indications

Indications

Open-angle glaucoma. Ocular hypertension.

Betagan Dosage and Administration

Adult

1–2 drops of 0.5% 1–2 times daily. Remove contact lenses prior to administration; may reinsert 15mins later.

Children

Not established.

Betagan Contraindications

Contraindications

Bronchial asthma. Severe COPD. Sinus bradycardia. 2^nd- or 3^rd-degree AV block. Overt cardiac failure. Cardiogenic shock.

Betagan Boxed Warnings

Not Applicable

Betagan Warnings/Precautions

Warnings/Precautions

Mild or moderate COPD, bronchospastic disease; not recommended. Impair compensatory tachycardia. Increase risk of hypotension. Diabetes. Hyperthyroidism. Choroidal detachment after filtration procedures. Diminished pulmonary function. Cerebrovascular insufficiency. Angle-closure glaucoma. Myasthenia. Withdraw gradually before surgery. Discontinue at first sign of cardiac failure. Vascular insufficiency (eg, Raynaud's phenomenon). Sulfite sensitivity. Pregnancy. Nursing mothers.

Betagan Pharmacokinetics

Metabolism

Hepatic.

Elimination

Half-life: 20 hours.

Betagan Interactions

Interactions

Additive effects with systemic β-blockers, digitalis, calcium blockers, reserpine, phenothiazine-related drugs. Mydriasis with epinephrine.

Betagan Adverse Reactions

Adverse Reactions

Transient ocular burning, stinging, blepharoconjunctivitis, bradycardia, hypotension, iridocyclitis, headache, transient ataxia, dizziness, lethargy, urticaria, pruritus, decreased corneal sensitivity; systemic absorption (bronchospasm, cardiac failure).

Betagan Clinical Trials

See Literature

Betagan Note