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Azopt Generic Name & Formulations
Legal Class
Rx
General Description
Brinzolamide 1%; oph. susp; contains benzalkonium chloride.
Pharmacological Class
Carbonic anhydrase inhibitor (sulfonamide).
How Supplied
Susp—10mL, 15mL
Manufacturer
Generic Availability
YES
Azopt Indications
Indications
Open-angle glaucoma. Ocular hypertension.
Azopt Dosage and Administration
Adult
1 drop 3 times daily.
Children
Not established.
Azopt Contraindications
Not Applicable
Azopt Boxed Warnings
Not Applicable
Azopt Warnings/Precautions
Warnings/Precautions
Severe renal impairment (CrCl <30mL/min): not recommended. Discontinue if serious systemic or hypersensitivity reactions occur. Low endothelial cell counts: increased risk for corneal edema. Acute angle-closure glaucoma. Soft contact lenses (remove; may reinsert 15mins after administration). Pregnancy. Nursing mothers.
Azopt Pharmacokinetics
See Literature
Azopt Interactions
Interactions
Concomitant oral carbonic anhydrase inhibitors: not recommended. Separate administration of other oph drugs by ≥10mins. Concomitant high-dose salicylate therapy may cause rare acid-base alterations.
Azopt Adverse Reactions
Adverse Reactions
Blurred vision, bitter/sour taste, blepharitis, dermatitis, dry eye, foreign body sensation, headache, hyperemia; ocular discharge, discomfort, or itch; keratitis, rhinitis.
Azopt Clinical Trials
See Literature
Azopt Note
Not Applicable
Azopt Patient Counseling
See Literature
