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Alphagan P Generic Name & Formulations
Legal Class
Rx
General Description
Brimonidine tartrate 0.1%, 0.15%; oph. soln; contains purite.
Pharmacological Class
Alpha-2 agonist.
How Supplied
Soln—5mL, 10mL, 15mL
Manufacturer
Alphagan P Indications
Indications
Open-angle glaucoma. Ocular hypertension.
Alphagan P Dosage and Administration
Adults and Children
<2yrs: not recommended. ≥2yrs: 1 drop every 8 hours.
Alphagan P Contraindications
Contraindications
Concomitant MAOIs.
Alphagan P Boxed Warnings
Not Applicable
Alphagan P Warnings/Precautions
Warnings/Precautions
Severe cardiovascular disease. Hepatic or renal impairment. Depression. Cerebral or coronary insufficiency. Raynaud's phenomenon. Orthostatic hypotension. Thromboangiitis obliterans. Remove soft contact lenses before use; may reinsert 15 minutes later. Monitor for loss of effect. Pregnancy (Cat.B). Nursing mothers: not recommended.
Alphagan P Pharmacokinetics
Elimination
Renal. Half-life: ~2 hours.
Alphagan P Interactions
Interactions
MAOIs: see Contraindications. Caution with CNS depressants, antihypertensives, cardiac glycosides, tricyclic antidepressants. Separate administration of other oph drugs by ≥5 minutes.
Alphagan P Adverse Reactions
Adverse Reactions
Oral dryness, ocular hyperemia, burning, stinging, headache, blurred or abnormal vision, foreign body sensation, fatigue, drowsiness, conjunctival follicles, ocular allergic reactions or pruritus, corneal staining/erosion, photophobia, ocular discomfort or dryness, tearing, upper respiratory symptoms, conjunctival blanching, muscular pain, others.
Alphagan P Clinical Trials
See Literature
Alphagan P Note
Not Applicable
Alphagan P Patient Counseling
See Literature
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