Panretin

— THERAPEUTIC CATEGORIES —
  • Kaposi's sarcoma

Panretin Generic Name & Formulations

General Description

Alitretinoin 0.1%; gel.

Pharmacological Class

Retinoid.

How Supplied

Gel—60g

Manufacturer

Panretin Indications

Indications

Cutaneous lesions of AIDS-related Kaposi's sarcoma (KS).

Panretin Dosage and Administration

Adult

Apply twice daily to lesions (avoid mucous membranes and normal skin); do not occlude; may increase to 3–4 times daily as tolerated. Reduce frequency or suspend treatment if local toxicity occurs.

Children

Not recommended.

Panretin Contraindications

Not Applicable

Panretin Boxed Warnings

Not Applicable

Panretin Warnings/Precautions

Warnings/Precautions

Not for use when systemic KS therapy required. Avoid sun, UV light. Flammable. Pregnancy (Cat.D), nursing mothers: not recommended.

Panretin Pharmacokinetics

See Literature

Panretin Interactions

Interactions

Increases DEET toxicity (avoid).

Panretin Adverse Reactions

Adverse Reactions

Photosensitivity, rash, pruritus, pain, exfoliative dermatitis, paresthesia, edema.

Panretin Clinical Trials

See Literature

Panretin Note

Not Applicable

Panretin Patient Counseling

See Literature