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Megestrol Tablets Generic Name & Formulations
Legal Class
Rx
General Description
Megestrol acetate 20mg, 40mg; scored tabs.
Pharmacological Class
Progestin.
How Supplied
Contact supplier.
Manufacturer
Megestrol Tablets Indications
Indications
Palliative treatment of advanced breast carcinoma.
Megestrol Tablets Dosage and Administration
Adult
40mg 4 times daily.
Children
Not applicable.
Megestrol Tablets Contraindications
Contraindications
Pregnancy.
Megestrol Tablets Boxed Warnings
Not Applicable
Megestrol Tablets Warnings/Precautions
Warnings/Precautions
History of thromboembolic disease. Diabetes. Monitor for adrenal insufficiency. Fetal toxicity. Obtain (–) pregnancy test prior to initiation. Advise females of reproductive potential to use effective contraception during therapy. Nursing mothers: not recommended.
Megestrol Tablets Pharmacokinetics
See Literature
Megestrol Tablets Interactions
Interactions
May increase insulin requirements. Decreases indinavir levels.
Megestrol Tablets Adverse Reactions
Adverse Reactions
Weight gain, thromboembolic events, heart failure, GI upset, edema, breakthrough menstrual bleeding, dyspnea, tumor flare, hyperglycemia, alopecia, hypertension, carpal tunnel syndrome, mood changes, hot flashes, malaise, asthenia, lethargy, sweating, rash.
Megestrol Tablets Clinical Trials
See Literature
Megestrol Tablets Note
Notes
Formerly known under the brand name Megace.
Megestrol Tablets Patient Counseling
See Literature
Megestrol Tablets Generic Name & Formulations
Legal Class
Rx
General Description
Megestrol acetate 20mg, 40mg; scored tabs.
Pharmacological Class
Progestin.
How Supplied
Contact supplier.
Manufacturer
Megestrol Tablets Indications
Indications
Palliative treatment of advanced endometrial carcinoma.
Megestrol Tablets Dosage and Administration
Adult
40–320mg daily in divided doses.
Children
Not applicable.
Megestrol Tablets Contraindications
Contraindications
Pregnancy.
Megestrol Tablets Boxed Warnings
Not Applicable
Megestrol Tablets Warnings/Precautions
Warnings/Precautions
History of thromboembolic disease. Diabetes. Monitor for adrenal insufficiency. Fetal toxicity. Obtain (–) pregnancy test prior to initiation. Advise females of reproductive potential to use effective contraception during therapy. Nursing mothers: not recommended.
Megestrol Tablets Pharmacokinetics
See Literature
Megestrol Tablets Interactions
Interactions
May increase insulin requirements. Decreases indinavir levels.
Megestrol Tablets Adverse Reactions
Adverse Reactions
Weight gain, thromboembolic events, heart failure, GI upset, edema, breakthrough menstrual bleeding, dyspnea, tumor flare, hyperglycemia, alopecia, hypertension, carpal tunnel syndrome, mood changes, hot flashes, malaise, asthenia, lethargy, sweating, rash.
Megestrol Tablets Clinical Trials
See Literature
Megestrol Tablets Note
Notes
Formerly known under the brand name Megace.
Megestrol Tablets Patient Counseling
See Literature
