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Casodex Generic Name & Formulations
Legal Class
Rx
General Description
Bicalutamide 50mg; tabs.
Pharmacological Class
Antiandrogen.
How Supplied
Tabs—30, 100
Manufacturer
Casodex Indications
Indications
In combination with luteinizing hormone-releasing hormone (LHRH) analogue in stage D2 metastatic prostate carcinoma.
Casodex Dosage and Administration
Adult
Take at the same time each day. 50mg daily. Start treatment at same time as starting LHRH analogue.
Children
Not applicable.
Casodex Contraindications
Contraindications
Women. Pregnancy.
Casodex Boxed Warnings
Not Applicable
Casodex Warnings/Precautions
Warnings/Precautions
Moderate to severe hepatic impairment. Monitor prostate specific antigen and hepatic function (discontinue if ALT >2xULN or if jaundice occurs). Males with female partners of reproductive potential should use effective contraception during therapy and for 130 days after final dose. Nursing mothers.
Casodex Pharmacokinetics
See Literature
Casodex Interactions
Interactions
Monitor oral anticoagulants.
Casodex Adverse Reactions
Adverse Reactions
Hot flashes, gynecomastia, breast pain, diarrhea, pain, asthenia, infection, dyspnea, impotence, loss of libido, others (see full labeling); rare: hepatitis.
Casodex Clinical Trials
See Literature
Casodex Note
Not Applicable
Casodex Patient Counseling
See Literature
