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Vandazole Generic Name & Formulations
Legal Class
Rx
General Description
Metronidazole 0.75%; vaginal gel; contains parabens.
Pharmacological Class
Antibacterial.
How Supplied
Gel—70g (w. applicators)
Manufacturer
Vandazole Indications
Indications
Bacterial vaginosis.
Vandazole Dosage and Administration
Adult
One applicatorful once daily at bedtime for 5 days.
Children
Pre-menarchal: not established.
Vandazole Contraindications
Not Applicable
Vandazole Boxed Warnings
Not Applicable
Vandazole Warnings/Precautions
Warnings/Precautions
Discontinue if abnormal neurological signs develop. CNS or hepatic disease. Do not have vaginal intercourse or use tampons or douches during therapy. Pregnancy. Nursing mothers: may interrupt breastfeeding; pump/discard breastmilk during and for 48hrs after the last dose.
Vandazole Pharmacokinetics
See Literature
Vandazole Interactions
Interactions
Avoid concomitant alcohol. Do not give within 2 weeks of disulfiram (possible psychotic reactions). May potentiate oral anticoagulants, lithium; monitor. May be potentiated by cimetidine. May interfere with serum chemistry tests.
Vandazole Adverse Reactions
Adverse Reactions
Fungal infection, headache, pruritus, abdominal pain, GI upset, dysmenorrhea, pharyngitis, rash, breast pain, metrorrhagia.
Vandazole Clinical Trials
See Literature
Vandazole Note
Not Applicable
Vandazole Patient Counseling
See Literature
