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Norethindrone Acetate Generic Name & Formulations
Legal Class
Rx
General Description
Norethindrone acetate 5mg; scored tabs.
Pharmacological Class
Progestin.
How Supplied
Contact supplier
Manufacturer
Norethindrone Acetate Indications
Indications
Endometriosis.
Norethindrone Acetate Dosage and Administration
Adult
Initially 5mg daily for 2 weeks, then increase by 2.5mg/day every 2 weeks up to 15mg/day maintenance dose. Continue for 6–9 months unless breakthrough bleeding is intolerable.
Children
Not applicable.
Norethindrone Acetate Contraindications
Contraindications
Thromboembolic disorders. Hepatic dysfunction. Undiagnosed vaginal bleeding. Breast or genital carcinoma. Missed abortion. Pregnancy (Cat.X).
Norethindrone Acetate Boxed Warnings
Not Applicable
Norethindrone Acetate Warnings/Precautions
Warnings/Precautions
Cardiac or renal dysfunction. Depression. Include Pap smear in pretreatment exam. Conditions aggravated by fluid retention. Discontinue if jaundice, visual disturbances, migraine, or thrombotic disorders occur. Nursing mothers.
Norethindrone Acetate Pharmacokinetics
See Literature
Norethindrone Acetate Interactions
Interactions
Rifampin may increase metabolism.
Norethindrone Acetate Adverse Reactions
Adverse Reactions
Menstrual and cervical changes, edema, jaundice, rash, depression, mastodynia, decreased glucose tolerance, weight changes, thromboembolic disease, breakthrough bleeding, melasma, chloasma.
Norethindrone Acetate Clinical Trials
See Literature
Norethindrone Acetate Note
Notes
Formerly known under the brand name Aygestin.
Norethindrone Acetate Patient Counseling
See Literature
Norethindrone Acetate Generic Name & Formulations
Legal Class
Rx
General Description
Norethindrone acetate 5mg; scored tabs.
Pharmacological Class
Progestin.
How Supplied
Contact supplier
Manufacturer
Norethindrone Acetate Indications
Indications
Secondary amenorrhea, abnormal uterine bleeding due to hormonal imbalance without organic pathology.
Norethindrone Acetate Dosage and Administration
Adult
2.5–10mg daily for 5–10 days during 2nd half of theoretical menstrual cycle after estrogens if needed.
Children
Not applicable.
Norethindrone Acetate Contraindications
Contraindications
Thromboembolic disorders. Hepatic dysfunction. Undiagnosed vaginal bleeding. Breast or genital carcinoma. Missed abortion. Pregnancy (Cat.X).
Norethindrone Acetate Boxed Warnings
Not Applicable
Norethindrone Acetate Warnings/Precautions
Warnings/Precautions
Cardiac or renal dysfunction. Depression. Include Pap smear in pretreatment exam. Conditions aggravated by fluid retention. Discontinue if jaundice, visual disturbances, migraine, or thrombotic disorders occur. Nursing mothers.
Norethindrone Acetate Pharmacokinetics
See Literature
Norethindrone Acetate Interactions
Interactions
Rifampin may increase metabolism.
Norethindrone Acetate Adverse Reactions
Adverse Reactions
Menstrual and cervical changes, edema, jaundice, rash, depression, mastodynia, decreased glucose tolerance, weight changes, thromboembolic disease, breakthrough bleeding, melasma, chloasma.
Norethindrone Acetate Clinical Trials
See Literature
Norethindrone Acetate Note
Notes
Formerly known under the brand name Aygestin.
Norethindrone Acetate Patient Counseling
See Literature
