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Menest Generic Name & Formulations
Legal Class
Rx
General Description
Esterified estrogens 0.3mg, 0.625mg, 1.25mg, 2.5mg; tabs.
Pharmacological Class
Estrogen.
How Supplied
Tabs 2.5mg—50; 0.3mg, 0.625mg, 1.25mg—100
Manufacturer
Menest Indications
Indications
Moderate to severe vasomotor symptoms of menopause. Atrophic vaginitis. Kraurosis vulvae. Hypoestrogenism.
Menest Dosage and Administration
Adult
Menopause: 1.25mg daily, give cyclically (3 weeks on, 1week off); if menstruating use Day 5 start. Atrophic vaginitis, kraurosis vulvae: 0.3–1.25mg or more daily, give cyclically (3 weeks on, 1 week off). Hypogonadism: 2.5–7.5mg daily in divided doses for 20 days then stop for 10 days; repeat course if withdrawal bleeding does not occur within these 10 days. If bleeding occurs within 10 days, begin 20-day cyclic regimen adding an oral progestin. If bleeding occurs before this regimen is finished, discontinue therapy and may resume on Day 5 of bleeding. Female castration, primary ovarian failure: 1.25mg daily, cyclically. Reevaluate periodically.
Children
Not applicable.
Menest Contraindications
Contraindications
Thrombophlebitis. Thromboembolic disorders. Cerebrovascular or coronary artery disease. Pregnancy (Cat.X).
Menest Boxed Warnings
Not Applicable
Menest Warnings/Precautions
Warnings/Precautions
Hepatic dysfunction. Gallbladder disease. Conditions aggravated by fluid retention. Familial hyperlipoproteinemia. Discontinue if jaundice occurs. Nursing mothers.
Menest Pharmacokinetics
See Literature
Menest Interactions
Not Applicable
Menest Adverse Reactions
Adverse Reactions
See literature. Breakthrough bleeding, dysmenorrhea, mastodynia, migraine, depression, edema, weight changes, hypertension, GI upset.
Menest Clinical Trials
See Literature
Menest Note
Not Applicable
Menest Patient Counseling
See Literature
Menest Generic Name & Formulations
Legal Class
Rx
General Description
Esterified estrogens 0.3mg, 0.625mg, 1.25mg, 2.5mg; tabs.
Pharmacological Class
Estrogen.
How Supplied
Tabs 2.5mg—50; 0.3mg, 0.625mg, 1.25mg—100
Manufacturer
Menest Indications
Indications
Palliative treatment of androgen-dependent advanced prostate cancer.
Menest Dosage and Administration
Adult
1.25–2.5mg 3 times daily.
Children
Not applicable.
Menest Contraindications
Contraindications
Thrombophlebitis. Thromboembolic disorders. Cerebrovascular or coronary artery disease. Pregnancy (Cat.X).
Menest Boxed Warnings
Not Applicable
Menest Warnings/Precautions
Warnings/Precautions
Hepatic dysfunction. Gallbladder disease. Conditions aggravated by fluid retention. Familial hyperlipoproteinemia. Discontinue if jaundice occurs. Nursing mothers.
Menest Pharmacokinetics
See Literature
Menest Interactions
Not Applicable
Menest Adverse Reactions
Adverse Reactions
See literature. Migraine, depression, edema, weight changes, hypertension, GI upset, gynecomastia, impotence.
Menest Clinical Trials
See Literature
Menest Note
Not Applicable
Menest Patient Counseling
See Literature
