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Kariva Generic Name & Formulations
Legal Class
Rx
General Description
Desogestrel 0.15 mg, ethinyl estradiol 20mcg (21 tabs); inert (2 tabs); ethinyl estradiol 10mcg (5 tabs).
Pharmacological Class
Progestin + estrogen.
How Supplied
Packs—6
Manufacturer
Kariva Indications
Indications
Oral contraception.
Kariva Dosage and Administration
Adult
Take in correct sequence at same time each day; max 24 hours between doses. 1 tab daily for 28 days; repeat.
Children
Not applicable.
Kariva Contraindications
Contraindications
Thrombophlebitis or thromboembolic disorders. Cerebral vascular or coronary artery disease. Breast or other estrogen-dependent neoplasms. Undiagnosed abnormal genital bleeding. Cholestatic jaundice of pregnancy or jaundice with prior OC use. Hepatic adenoma or carcinoma. Pregnancy (Cat.X).
Kariva Boxed Warnings
Not Applicable
Kariva Warnings/Precautions
Warnings/Precautions
Smokers over 35 years of age: not recommended. Uncontrolled hypertension. Hypertriglyceridemia. Discontinue if jaundice, visual disturbances, migraine or other severe headaches occur. Do regular complete physical exams. May need barrier contraception with Sunday starts or postpartum use (see literature). Nursing mothers: not recommended.
Kariva Pharmacokinetics
See Literature
Kariva Interactions
Interactions
Antagonized by hepatic enzyme inducing drugs (eg, rifampin, griseofulvin, St. John's wort), possibly others. May affect measurement of sex hormone-binding globulin levels.
Kariva Adverse Reactions
Adverse Reactions
Hypertension, nausea, vomiting, breakthrough bleeding, amenorrhea, transient delay of ovulation after discontinuation, edema, chloasma, mastodynia, headache, intolerance to contact lenses. Increased risk of gallbladder disease, thromboembolic disorders.
Kariva Clinical Trials
See Literature
Kariva Note
Not Applicable
Kariva Patient Counseling
See Literature
