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Junel 24 Fe Generic Name & Formulations
Legal Class
Rx
General Description
Norethindrone acetate 1mg, ethinyl estradiol 20mcg (24 light yellow tabs); inert+ (4 tabs); +contains ferrous fumarate 75mg.
Pharmacological Class
Progestin + estrogen.
How Supplied
Blister cards—3
Manufacturer
Junel 24 Fe Indications
Indications
Oral contraception.
Junel 24 Fe Dosage and Administration
Adult
1 tab daily for 28 days; repeat.
Children
Premenarchal: not recommended.
Junel 24 Fe Contraindications
Contraindications
Thrombophlebitis or thromboembolic disease. History of DVT, cerebrovascular or coronary artery disease. Thrombogenic valvular disease. Severe hypertension. Diabetes with vascular disease. Headaches with focal neurologic symptoms. Major surgery with prolonged immobilization. Known or suspected breast carcinoma, endometrial or other estrogen-dependent neoplasia. Undiagnosed abnormal genital bleeding. Pregnancy-related cholestasis. Hepatic disease or tumors. Pregnancy (Cat.X).
Junel 24 Fe Boxed Warnings
Boxed Warning
Cigarette smoking increases risk of serious cardiovascular events.
Junel 24 Fe Warnings/Precautions
Warnings/Precautions
Increased risk of cardiovascular events esp. in cigarette smokers >35yrs of age; not recommended. Discontinue if thrombotic event, unexplained visual changes, jaundice, or headache/migraine occurs, and at least 4 weeks before through 2 weeks after surgery associated with increased risk of thromboembolism, and during and after prolonged immobilization. Cardio- or cerebrovascular diseases. Gallbladder disease. Obesity. Diabetes. Prediabetes. Hypertriglyceridemia. Depression. Conditions aggravated by fluid retention; monitor. Evaluate significant changes in headaches, irregular uterine bleeding, amenorrhea, retinal vein thrombosis. Monitor BP. Do regular complete physical exams. Nursing mothers: not recommended.
Junel 24 Fe Pharmacokinetics
See Literature
Junel 24 Fe Interactions
Interactions
May be antagonized by anti-infectives and anticonvulsants (eg, phenytoin, phenylbutazone, barbiturates, carbamazepine, felbamate, griseofulvin, oxcarbazepine, rifampin, topiramate), St. John’s wort; use backup contraception. May be potentiated by atorvastatin, acetaminophen, ascorbic acid, or CYP3A4 inhibitors (eg, itraconazole, ketoconazole). May be affected by HIV protease inhibitors. May antagonize acetaminophen, temazepam, salicylic acid, morphine, clofibric acid. May potentiate cyclosporine, prednisolone, theophylline. May affect laboratory tests (eg, coagulation factors, lipids, glucose tolerance, binding proteins, serum folate).
Junel 24 Fe Adverse Reactions
Adverse Reactions
Headache, vaginal candidiasis, upper respiratory tract infection, nausea, menstrual cramps, breast tenderness, sinusitis, bacterial vaginitis, abnormal cervical smear, acne, UTI, mood swings, weight gain, vomiting, metrorrhagia; serious cardiovascular events and stroke, vascular events, hypertension, irregular uterine bleeding, liver disease.
Junel 24 Fe Clinical Trials
See Literature
Junel 24 Fe Note
Not Applicable
Junel 24 Fe Patient Counseling
See Literature
