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Cervidil Generic Name & Formulations
Legal Class
Rx
General Description
Dinoprostone 10mg; controlled-release vaginal insert w. retrieval system.
How Supplied
Insert—1
Manufacturer
Cervidil Indications
Indications
Cervical ripening in patients at or near term when there is an indication for labor induction.
Cervidil Dosage and Administration
Adult
See full labeling.
Children
Not established.
Cervidil Contraindications
Contraindications
Evidence or suspicion of fetal distress where delivery is not imminent. Unexplained vaginal bleeding. Evidence or suspicion of marked cephalopelvic disproportion. Conditions for which labor induction, oxytocics are inappropriate or prolonged uterine contractions may be detrimental to fetal safety. Previous cesarean section or other uterine surgery expected to affect uterine integrity (eg, myomectomy). Six or more previous term pregnancies. Concomitant IV oxytocics.
Cervidil Boxed Warnings
Not Applicable
Cervidil Warnings/Precautions
Warnings/Precautions
For hospital use when appropriate obstetric care is present. Increased risk of postpartum disseminated intravascular coagulation (eg, ≥30yrs of age, complications during pregnancy, gestational age >40weeks); assess for evolving fibrinolysis in the immediate postpartum period. Monitor for amniotic fluid embolism syndrome. Glaucoma. Monitor uterine activity, fetal status, cervical dilatation/effacement. Remove insert if uterine tachysystole, uterine hypersystole/hypertonicity, fetal distress, or if labor commences, and prior to amniotomy or following rupture of membranes. Pregnancy.
Cervidil Pharmacokinetics
See Literature
Cervidil Interactions
Interactions
Potentiates oxytocics; delay administration of oxytocics at least 30mins after removal of insert.
Cervidil Adverse Reactions
Adverse Reactions
Uterine tachysystole with/without fetal distress, fetal distress without uterine tachysystole.
Cervidil Clinical Trials
See Literature
Cervidil Note
Not Applicable
Cervidil Patient Counseling
See Literature
