Nutrilipid

Individualize. Dose based on patient’s energy requirements, body wt, tolerance, clinical status, age-related growth rate in children, and ability to eliminate and metabolize fat. Administer by IV infusion via peripheral or central line. Preterm and term infants to 10yrs: initially 1–2g/kg/day; max 3g/kg/day. Initiate rate at 0.05mL/min for the first 10–15mins; increase gradually to required rate after 15mins (max 0.75mL/kg/hr). 11–<17yrs: initially 1g/kg/day; max 2.5g/kg/day. Initiate rate at 0.05mL/min for the first 10–15mins; increase gradually to required rate after 15mins (max 0.5mL/kg/hr). ≥17yrs: initially 1–1.5g/kg/day; max 2.5g/kg/day. Initiate rate at 0.5mL/min for the first 15–30mins; increase gradually to required rate after 30mins (max 0.5mL/kg/hr). Usual infusion duration: 12–24 hours; may continue treatment based on patient’s clinical status. If serum triglycerides (>400mg/dL): initiate at a lower dose and increase in smaller increments; check levels before each adjustment. For complete parenteral nutrition: supplement with amino acids, carbohydrates, electrolytes, vitamins and trace elements.