Megestrol Oral Suspension

— THERAPEUTIC CATEGORIES —
  • Anorexia/cachexia

Megestrol Oral Suspension Generic Name & Formulations

General Description

Megestrol acetate 40mg/mL; lemon-lime flavor.

Pharmacological Class

Progestin.

How Supplied

Contact supplier.

Megestrol Oral Suspension Indications

Indications

Anorexia, cachexia, or unexplained significant weight loss in patients diagnosed with AIDS.

Megestrol Oral Suspension Dosage and Administration

Adult

Initially 800mg/day.

Children

Not established.

Megestrol Oral Suspension Contraindications

Contraindications

Pregnancy.

Megestrol Oral Suspension Boxed Warnings

Not Applicable

Megestrol Oral Suspension Warnings/Precautions

Warnings/Precautions

Do not substitute with other megestrol suspensions (not interchangeable). History of thromboembolic disease. Monitor for signs/symptoms of adrenal insufficiency; consider empiric therapy if occurs. Diabetes. Renal impairment. Elderly. Fetal toxicity. Obtain (–) pregnancy test prior to initiation. Advise females of reproductive potential to use effective contraception during therapy. Nursing mothers: not recommended.

Megestrol Oral Suspension Pharmacokinetics

See Literature

Megestrol Oral Suspension Interactions

Interactions

May increase insulin requirements. Monitor INR closely with warfarin.

Megestrol Oral Suspension Adverse Reactions

Adverse Reactions

GI upset, impotence, flatulence, rash, hypertension, fever, decreased libido, breakthrough bleeding, hyperglycemia, insomnia.

Megestrol Oral Suspension Clinical Trials

See Literature

Megestrol Oral Suspension Note

Not Applicable

Megestrol Oral Suspension Patient Counseling

See Literature