Megestrol Oral Suspension Generic Name & Formulations
Legal Class
Rx
General Description
Megestrol acetate 40mg/mL; lemon-lime flavor.
Pharmacological Class
Progestin.
How Supplied
Contact supplier.
Manufacturer
Megestrol Oral Suspension Indications
Indications
Anorexia, cachexia, or unexplained significant weight loss in patients diagnosed with AIDS.
Megestrol Oral Suspension Dosage and Administration
Adult
Initially 800mg/day.
Children
Not established.
Megestrol Oral Suspension Contraindications
Contraindications
Pregnancy.
Megestrol Oral Suspension Boxed Warnings
Not Applicable
Megestrol Oral Suspension Warnings/Precautions
Warnings/Precautions
Do not substitute with other megestrol suspensions (not interchangeable). History of thromboembolic disease. Monitor for signs/symptoms of adrenal insufficiency; consider empiric therapy if occurs. Diabetes. Renal impairment. Elderly. Fetal toxicity. Obtain (–) pregnancy test prior to initiation. Advise females of reproductive potential to use effective contraception during therapy. Nursing mothers: not recommended.
Megestrol Oral Suspension Pharmacokinetics
See Literature
Megestrol Oral Suspension Interactions
Interactions
May increase insulin requirements. Monitor INR closely with warfarin.
Megestrol Oral Suspension Adverse Reactions
Adverse Reactions
GI upset, impotence, flatulence, rash, hypertension, fever, decreased libido, breakthrough bleeding, hyperglycemia, insomnia.
Megestrol Oral Suspension Clinical Trials
See Literature
Megestrol Oral Suspension Note
Not Applicable
Megestrol Oral Suspension Patient Counseling
See Literature