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Megace Es Generic Name & Formulations
Legal Class
Rx
General Description
Megestrol acetate 125mg/mL; oral susp; lemon-lime flavor.
Pharmacological Class
Progestin.
How Supplied
Concentrated susp (125mg/mL)—5oz
Manufacturer
Generic Availability
YES
Megace Es Indications
Indications
Anorexia, cachexia, or unexplained significant weight loss in patients diagnosed with AIDS.
Limitations of Use
Should only be instituted after treatable causes of weight loss are sought and addressed. Not for prophylactic use to avoid weight loss.
Megace Es Dosage and Administration
Adult
625mg/5mL per day.
Children
Not established.
Megace Es Contraindications
Contraindications
Pregnancy.
Megace Es Boxed Warnings
Not Applicable
Megace Es Warnings/Precautions
Warnings/Precautions
Do not substitute with other megestrol suspensions (not interchangeable). History of thromboembolic disease. Monitor for signs/symptoms of adrenal insufficiency; consider empiric therapy if occurs. Diabetes. Renal impairment. Elderly. Fetal toxicity. Obtain (–) pregnancy test prior to initiation. Advise females of reproductive potential to use effective contraception during therapy. Nursing mothers: not recommended.
Megace Es Pharmacokinetics
See Literature
Megace Es Interactions
Interactions
May increase insulin requirements. Decreases indinavir levels.
Megace Es Adverse Reactions
Adverse Reactions
Nausea, diarrhea, impotence, rash, flatulence, hypertension, asthenia; rare: adrenal insufficiency, breakthrough bleeding.
Megace Es Clinical Trials
See Literature
Megace Es Note
Not Applicable
Megace Es Patient Counseling
See Literature
