Ztalmy Generic Name & Formulations
Legal Class
General Description
Pharmacological Class
How Supplied
Manufacturer
Generic Availability
Mechanism of Action
Ztalmy Indications
Indications
Ztalmy Dosage and Administration
Adults and Children
<2yrs: not established. Take with food. Give 3 times daily in equally divided doses using oral syringe. ≥2yrs (≤28kg; dose based on body wt.): initially 18mg/kg/day for Days 1–7; 33mg/kg/day for Days 8–14; 48mg/kg/day for Days 15–21; then 63mg/kg/day thereafter; (>28kg): initially 450mg/day for Days 1–7; 900mg/day for Days 8–14; 1350mg/day for Days 15–21; then 1800mg/day thereafter. Severe hepatic impairment (Child-Pugh class C): (≤28kg; dose based on body wt.): initially 6mg/kg/day for Days 1–7; 11mg/kg/day for Days 8–14; 16mg/kg/day for Days 15–21; then 21mg/kg/day thereafter; (>28kg): initially 150mg/day for Days 1–7; 300mg/day for Days 8–14; 450mg/day for Days 15–21; then 600mg/day thereafter.
Ztalmy Contraindications
Not Applicable
Ztalmy Boxed Warnings
Not Applicable
Ztalmy Warnings/Precautions
Warnings/Precautions
Monitor for somnolence and sedation. Monitor for depression, suicidal thoughts or behavior, or any unusual changes in mood or behavior. Avoid abrupt cessation. Withdraw gradually. Severe hepatic impairment (Child-Pugh class C): dose adjustment needed. Pregnancy. Nursing mothers.
Ztalmy Pharmacokinetics
Absorption
Time to maximum plasma concentration (Tmax): 2–3 hours.
Distribution
Plasma protein bound: ~99%.
Elimination
Ztalmy Interactions
Interactions
Ztalmy Adverse Reactions
Adverse Reactions
Ztalmy Clinical Trials
See Literature
Ztalmy Note
Not Applicable
Ztalmy Patient Counseling
See Literature