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Trihexyphenidyl Elixir Generic Name & Formulations
Legal Class
Rx
General Description
Trihexyphenidyl HCl 2mg/5mL; lime-mint flavor; contains alcohol.
Pharmacological Class
Anticholinergic.
See Also
How Supplied
Contact supplier.
Manufacturer
Trihexyphenidyl Elixir Indications
Indications
Adjunct in Parkinsonism. Drug-induced extrapyramidal symptoms (EPS).
Trihexyphenidyl Elixir Dosage and Administration
Adult
Take with food. Give in 3–4 divided doses. Parkinsonism: 1mg on day 1, may increase by 2mg every 3–5 days; usual max 6–15mg/day. Concomitant levodopa: 3–6mg/day and reduce levodopa dose. EPS: 1mg on day 1; range 5–15mg/day.
Children
Not recommended.
Trihexyphenidyl Elixir Contraindications
Contraindications
Tardive dyskinesia. Narrow-angle glaucoma.
Trihexyphenidyl Elixir Boxed Warnings
Not Applicable
Trihexyphenidyl Elixir Warnings/Precautions
Warnings/Precautions
Cardiovascular, renal, or hepatic disorders. Hypertension. Psychosis. GI or GU obstruction. Exposure to extreme heat. Monitor intraocular pressure. Avoid abrupt cessation. Nursing mothers.
Trihexyphenidyl Elixir Pharmacokinetics
See Literature
Trihexyphenidyl Elixir Interactions
Interactions
Potentiates CNS depression with alcohol, CNS depressants. Antagonizes psychotropics. Additive anticholinergic effects with MAOIs. Paralytic ileus with phenothiazines, tricyclic antidepressants.
Trihexyphenidyl Elixir Adverse Reactions
Adverse Reactions
Anticholinergic and antihistaminic effects, confusion, anhidrosis, excitement, nausea, vomiting, angle-closure glaucoma, hallucinations, neuroleptic malignant syndrome, heat stroke, drowsiness.
Trihexyphenidyl Elixir Clinical Trials
See Literature
Trihexyphenidyl Elixir Note
Notes
Formerly known under the brand name Artane.
Trihexyphenidyl Elixir Patient Counseling
See Literature
