Radicava Generic Name & Formulations
Legal Class
Rx
General Description
Edaravone 30mg/100mL; soln for IV infusion; contains sodium bisulfite.
Pharmacological Class
Free radical scavenger.
See Also
How Supplied
Single-dose bags—1, 2; ORS Starter Kit (2×35mL)—1 (w. supplies); ORS Kit (1×50mL)—1 (w. supplies)
Manufacturer
Generic Availability
NO
Radicava Indications
Indications
Amyotrophic lateral sclerosis (ALS).
Radicava Dosage and Administration
Adult
Give as IV infusion over 60mins. Initial cycle: 60mg (given as two consecutive 30mg infusions) daily for 14 days, followed by 14 days off. Subsequent cycles: 60mg daily for 10 days out of 14-day periods, followed by 14 days off. Switching to ORS: use same dosing frequency.
Children
Not established.
Radicava Contraindications
Not Applicable
Radicava Boxed Warnings
Not Applicable
Radicava Warnings/Precautions
Warnings/Precautions
Monitor for hypersensitivity reactions; discontinue and treat if occur. Asthma. Sulfite sensitivity. Pregnancy. Nursing mothers.
Radicava Pharmacokinetics
See Literature
Radicava Interactions
Not Applicable
Radicava Adverse Reactions
Adverse Reactions
Contusion, gait disturbance, headache, dermatitis, eczema, respiratory failure/disorders, hypoxia, glycosuria, tinea infection; hypersensitivity reactions, anaphylaxis.
Radicava Clinical Trials
See Literature
Radicava Note
Not Applicable
Radicava Patient Counseling
See Literature