Zilretta

Not interchangeable with other injectable triamcinolone acetonide formulations. For intra-articular injection only. Not for epidural or intrathecal use; serious neurologic events may occur. Not suitable for use in small joints (eg, hand). Previously infected or unstable joints: not recommended. Increased risk of infections (viral, bacterial, fungal, protozoan, or helminthic). May mask signs of current infection. Avoid exposure to chickenpox or measles if unvaccinated. HPA axis suppression. Adrenal insufficiency. Supplement with additional corticosteroids in physiologic stress (eg, trauma, surgery, illness). Hypo- or hyperthyroidism. Patients with CHF, hypertension, renal insufficiency: monitor; dietary salt restriction and K⁺ supplementation may be necessary. Elevated intraocular pressure (monitor). Increased GI perforation risk in those with active or latent peptic ulcers, diverticulosis, diverticulitis, ulcerative colitis, intestinal anastomoses; avoid. Increased osteoporosis risk (eg, postmenopausal women). Emotional instability or psychiatric disorder; monitor for new or worsening behavior or mood disturbances. Pregnancy. Nursing mothers.