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Triluron Generic Name & Formulations
Legal Class
Rx
General Description
Sodium hyaluronate 20mg/2mL; soln for intra-articular inj.
Pharmacological Class
Hyaluronan.
How Supplied
Single-use vials—1; Single-use prefilled syringes—1
Manufacturer
Generic Availability
NO
Triluron Indications
Indications
Treatment of pain in osteoarthritis of the knee in patients who have failed nonpharmacologic therapy and analgesics (eg, acetaminophen).
Triluron Dosage and Administration
Adult
Prior to treatment: remove joint effusion (use separate syringe), if present; and give local anesthetic (eg, lidocaine) by SC inj. Inject 2mL intra-articularly in each affected knee weekly for 3 weeks. Use separate vial/syringe for each knee.
Children
Not established.
Triluron Contraindications
Contraindications
Infection or skin disease at inj site.
Triluron Boxed Warnings
Not Applicable
Triluron Warnings/Precautions
Warnings/Precautions
Treatment cycle <3 injections: not established. Avian protein, feather, egg allergy. Avoid strenuous activity within 48hrs after injection. Pregnancy. Nursing mothers.
Triluron Pharmacokinetics
See Literature
Triluron Interactions
Interactions
Avoid disinfectants with quaternary ammonium salts. Concomitant other intra-articular injectables: not recommended.
Triluron Adverse Reactions
Adverse Reactions
Gastrointestinal complaints, inj site pain, headache, local skin reactions, knee swelling/effusion, pruritus; transient knee inflammation.
Triluron Clinical Trials
See Literature
Triluron Note
Not Applicable
Triluron Patient Counseling
See Literature
