Share on Facebook
Share on Twitter
Share on LinkedIn
Share by Email
Print
Synvisc One Generic Name & Formulations
Legal Class
Rx
General Description
Hylan G-F 20 (hylan A and hylan B) 48mg; per 6mL; soln for intra-articular inj.
Pharmacological Class
Hyaluronan derivative.
How Supplied
Single-use syringe—1
Manufacturer
Generic Availability
NO
Synvisc One Indications
Indications
Treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy and simple analgesics (eg, acetaminophen).
Synvisc One Dosage and Administration
Adult
Remove synovial fluid or effusion before inj. Give as a single intra-articular inj. 6mL in one knee only.
Children
Not recommended.
Synvisc One Contraindications
Contraindications
Knee joint infections. Skin diseases or infections in area of the inj site.
Synvisc One Boxed Warnings
Not Applicable
Synvisc One Warnings/Precautions
Warnings/Precautions
Avian protein, feathers, or egg allergy. Severely inflamed knee joints. Lymphatic or venous stasis in leg. Advise patients to avoid strenuous activities for approx. 48 hrs following inj. Pregnancy, nursing mothers: not established.
Synvisc One Pharmacokinetics
See Literature
Synvisc One Interactions
Interactions
Avoid use of disinfectants containing quaternary ammonium salts; hyaluronan can precipitate in their presence. Concomitant other intra-articular inj: not studied.
Synvisc One Adverse Reactions
Adverse Reactions
Arthralgia, arthritis, arthropathy, inj site pain, gait disturbance; joint effusion, stiffness, swelling, warmth, pain.
Synvisc One Clinical Trials
See Literature
Synvisc One Note
Not Applicable
Synvisc One Patient Counseling
See Literature
