Salsalate Generic Name & Formulations
Legal Class
Rx
General Description
Salsalate 500mg, 750mg; scored tabs.
Pharmacological Class
Salicylate.
See Also
How Supplied
Contact supplier.
Manufacturer
Salsalate Indications
Indications
Rheumatoid arthritis. Osteoarthritis.
Salsalate Dosage and Administration
Adult
3g daily in divided doses.
Children
Not recommended.
Salsalate Contraindications
Contraindications
Varicella or influenza in teenagers. 3rd trimester pregnancy. Aspirin allergy. Coronary artery bypass graft surgery.
Salsalate Boxed Warnings
Not Applicable
Salsalate Warnings/Precautions
Warnings/Precautions
Advanced renal disease: not recommended. Impaired renal or hepatic function. Hypertension. Heart failure. Edema. Bleeding disorders. Monitor blood, liver, renal function with chronic use. Peptic ulcer. Gastritis. Diabetes. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended.
Salsalate Pharmacokinetics
See Literature
Salsalate Interactions
Interactions
PABA may increase serum levels. May potentiate anticoagulants, hypoglycemics, methotrexate. Urinary alkalinizers, antacids, corticosteroids may increase excretion. May antagonize uricosurics and spironolactone.
Salsalate Adverse Reactions
Adverse Reactions
Salicylism, tinnitus, nausea, dyspepsia, GI bleed, hearing loss, rash (discontinue if occurs). See literature re: risk of cardiovascular events.
Salsalate Clinical Trials
See Literature
Salsalate Note
Notes
Formerly known under the brand names Disalcid, Salflex.
Salsalate Patient Counseling
See Literature