Mytelase

— THERAPEUTIC CATEGORIES —
  • Myasthenia gravis

Mytelase Generic Name & Formulations

General Description

Ambenonium chloride 10mg; tabs.

Pharmacological Class

Cholinesterase inhibitor.

How Supplied

Tabs—100

Manufacturer

Mytelase Indications

Indications

Myasthenia gravis.

Mytelase Dosage and Administration

Adult

Individualize. Usual range: 5–25mg 3 or 4 times daily. Increase gradually at intervals of 1–2 days. Some patients may require 50–75mg per dose. Increasing dosage above 200mg daily requires supervision by clinician aware of signs and treatment of overdose.

Children

Not established.

Mytelase Contraindications

Contraindications

Concomitant atropine, mecamylamine, or any other ganglionic blocking agents.

Mytelase Boxed Warnings

Not Applicable

Mytelase Warnings/Precautions

Warnings/Precautions

Monitor closely; narrow margin between first appearance of side effects and serious toxic effects. Asthma. Parkinson's disease. Mechanical intestinal or urinary obstruction. Bradycardia. Cardiac conduction disorders. Elderly. Pregnancy. Nursing mothers: not recommended.

Mytelase Pharmacokinetics

See Literature

Mytelase Interactions

Interactions

See Contraindications.

Mytelase Adverse Reactions

Adverse Reactions

Overdosage (eg, excessive salivation, abdominal cramps, diarrhea, miosis, urinary urgency, sweating, nausea, increase in bronchial and lacrymal secretions, vomiting, muscle cramps, fasciculation of voluntary muscles, generalized malaise, anxiety, vertigo).

Mytelase Clinical Trials

See Literature

Mytelase Note

Not Applicable

Mytelase Patient Counseling

See Literature