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Miacalcin Injection Generic Name & Formulations
Legal Class
Rx
General Description
Calcitonin-salmon 200 IU/mL; soln for SC or IM inj.
Pharmacological Class
Hormone.
How Supplied
Multi-dose vials (2mL)—1
Manufacturer
Miacalcin Injection Indications
Indications
Paget's disease of bone. Hypercalcemia. Postmenopausal osteoporosis in women >5yrs postmenopausal.
Miacalcin Injection Dosage and Administration
Adult
Give by IM inj across multiple sites if total dose >2mL. Paget's: 100 IU SC or IM daily. Hypercalcemia: initially 4 IU/kg SC or IM every 12hrs, may increase after 1–2 days to 8 IU/kg every 12hrs, and then after 2 more days to max 8 IU/kg every 6hrs. Postmenopausal osteoporosis: 100 IU SC or IM daily.
Children
Not established.
Miacalcin Injection Contraindications
Not Applicable
Miacalcin Injection Boxed Warnings
Not Applicable
Miacalcin Injection Warnings/Precautions
Warnings/Precautions
Correct hypocalcemia and other mineral metabolism disorders before initiating; monitor serum calcium and hypocalcemia symptoms during therapy. Increased risk of malignancies. Consider periodic exams of urine sediment; serum alkaline phosphatase and urinary hydroxyproline in Paget's. Postmenopausal osteoporosis: supplement diet with calcium 1g/day and Vit.D 400 IU/day. Re-evaluate periodically. Pregnancy. Nursing mothers.
Miacalcin Injection Pharmacokinetics
See Literature
Miacalcin Injection Interactions
Interactions
May antagonize lithium (consider lithium dose adjustment).
Miacalcin Injection Adverse Reactions
Adverse Reactions
Nausea, vomiting, local inflammation, flushing, rash; hypersensitivity reactions, anaphylaxis, hypocalcemia, antibody formation.
Miacalcin Injection Clinical Trials
See Literature
Miacalcin Injection Note
Not Applicable
Miacalcin Injection Patient Counseling
See Literature
