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Lyvispah Generic Name & Formulations
Legal Class
Rx
General Description
Baclofen 5mg, 10mg, 20mg; oral granules; strawberry-flavor.
Pharmacological Class
Muscle relaxant (central).
How Supplied
Single-dose packets—90
Manufacturer
Generic Availability
NO
Lyvispah Indications
Indications
Spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity. May also be of some value in patients with spinal cord injuries and other spinal cord diseases.
Limitations of Use
Not for treatment of skeletal muscle spasm resulting from rheumatic disorders.
Lyvispah Dosage and Administration
Adult
Allow granules to dissolve in the mouth or can be swallowed. Also, can mix contents (1 packet) with up to 15mL of liquid or soft foods (eg, applesauce, yogurt, or pudding) if needed for administration within 2hrs. If multiple packets are required, each packet must be mixed with a separate volume of liquid or soft food. May also administer via enteral feeding tubes. Start with lowest dose possible; adjust based on response and tolerability. Initially 5mg 3 times daily for 3 days. May increase by increments of 5mg 3 times daily every 3 days, as needed; up to max 80mg daily.
Children
<12yrs: not established.
Lyvispah Contraindications
Not Applicable
Lyvispah Boxed Warnings
Not Applicable
Lyvispah Warnings/Precautions
Warnings/Precautions
Avoid abrupt cessation. Withdraw gradually during discontinuation. Stroke. Psychotic disorders. Schizophrenia. Confusional states. Autonomic dysreflexia. Epilepsy. Beneficial spasticity. Renal impairment. Elderly. Neonatal withdrawal symptoms; gradually reduce dose and discontinue treatment prior to delivery. Pregnancy. Nursing mothers.
Lyvispah Pharmacokinetics
See Literature
Lyvispah Interactions
Interactions
Additive CNS depression with alcohol, other CNS depressants.
Lyvispah Adverse Reactions
Adverse Reactions
Drowsiness, dizziness, weakness, nausea, confusion, hypotension, headache, insomnia, constipation, urinary frequency, fatigue; ovarian cysts, seizures and hallucinations on abrupt withdrawal.
Lyvispah Clinical Trials
See Literature
Lyvispah Note
Not Applicable
Lyvispah Patient Counseling
See Literature
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