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Ibuprofen Generic Name & Formulations
Legal Class
Rx
General Description
Ibuprofen 400mg, 600mg, 800mg; tabs.
Pharmacological Class
NSAID (propionic acid deriv.).
See Also
How Supplied
Contact supplier.
Manufacturer
Ibuprofen Indications
Indications
Rheumatoid arthritis (RA). Osteoarthritis (OA). Juvenile arthritis (JRA).
Ibuprofen Dosage and Administration
Adult
RA, OA: 400–800mg 3–4 times daily; max 3.2g/day.
Children
JRA: 30–40mg/kg per day in 3–4 doses. May use 20mg/kg per day in 3–4 doses for milder disease.
Ibuprofen Contraindications
Contraindications
Aspirin allergy. 3rd trimester pregnancy. Coronary artery bypass graft surgery.
Ibuprofen Boxed Warnings
Not Applicable
Ibuprofen Warnings/Precautions
Warnings/Precautions
Advanced renal disease: not recommended. History of upper GI disease. Active peptic ulcer. Impaired renal or hepatic function. Edema. Hypertension. Cardiac failure. Bleeding disorders. Diabetes. Monitor blood, hepatic, renal, and ocular function in chronic use. Discontinue if visual or liver dysfunction occurs. Dehydration. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended.
Ibuprofen Pharmacokinetics
See Literature
Ibuprofen Interactions
Interactions
Avoid aspirin. May increase bleeding with anticoagulants. Increases serum lithium levels. May increase toxicity of methotrexate. May decrease effect of furosemide, thiazide diuretics. Increased risk of GI bleed with alcohol.
Ibuprofen Adverse Reactions
Adverse Reactions
Peptic ulcer or perforation, GI bleeding, vision disorders, nausea, epigastric pain, heartburn, dizziness, rash (discontinue if occurs), edema, renal papillary necrosis, jaundice, hepatitis. See literature re: risk of cardiovascular events.
Ibuprofen Clinical Trials
See Literature
Ibuprofen Note
Not Applicable
Ibuprofen Patient Counseling
See Literature
Ibuprofen Generic Name & Formulations
Legal Class
Rx
General Description
Ibuprofen 400mg, 600mg, 800mg; tabs.
Pharmacological Class
NSAID (propionic acid deriv.).
See Also
How Supplied
Contact supplier.
Manufacturer
Ibuprofen Indications
Indications
Dysmenorrhea.
Ibuprofen Dosage and Administration
Adult
400mg every 4 hours; max 3.2g/day. May take with food or milk.
Children
Not applicable.
Ibuprofen Contraindications
Contraindications
Aspirin allergy. 3rd trimester pregnancy. Coronary artery bypass graft surgery.
Ibuprofen Boxed Warnings
Not Applicable
Ibuprofen Warnings/Precautions
Warnings/Precautions
Advanced renal disease: not recommended. History of upper GI disease. Active peptic ulcer. Impaired renal or hepatic function. Edema. Hypertension. Cardiac failure. Bleeding disorders. Diabetes. Monitor blood, hepatic, renal, and ocular function in chronic use. Discontinue if visual or liver dysfunction occurs. Dehydration. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended.
Ibuprofen Pharmacokinetics
See Literature
Ibuprofen Interactions
Interactions
Avoid aspirin. May increase bleeding with anticoagulants. Increases serum lithium levels. May increase toxicity of methotrexate. May decrease effect of furosemide, thiazide diuretics. Increased risk of GI bleed with alcohol.
Ibuprofen Adverse Reactions
Adverse Reactions
Peptic ulcer or perforation, GI bleeding, vision disorders, nausea, epigastric pain, heartburn, dizziness, rash (discontinue if occurs), edema, renal papillary necrosis, jaundice, hepatitis. See literature re: risk of cardiovascular events.
Ibuprofen Clinical Trials
See Literature
Ibuprofen Note
Not Applicable
Ibuprofen Patient Counseling
See Literature
Ibuprofen Generic Name & Formulations
Legal Class
Rx
General Description
Ibuprofen 400mg, 600mg, 800mg; tabs.
Pharmacological Class
NSAID (propionic acid deriv.).
See Also
How Supplied
Contact supplier.
Manufacturer
Ibuprofen Indications
Indications
Mild to moderate pain. Fever.
Ibuprofen Dosage and Administration
Adult
Pain: 400mg every 4–6 hrs as needed.
Children
Use caplets, chewables, suspension, or drops. <6 months: not recommended. ≥6 months: Fever <102.5°F: 5mg/kg every 6–8 hours. Fever >102.5°F or pain: 10mg/kg every 6–8 hours; max 40mg/kg/day.
Ibuprofen Contraindications
Contraindications
Aspirin allergy. 3rd trimester pregnancy. Coronary artery bypass graft surgery.
Ibuprofen Boxed Warnings
Not Applicable
Ibuprofen Warnings/Precautions
Warnings/Precautions
Advanced renal disease: not recommended. History of upper GI disease. Active peptic ulcer. Impaired renal or hepatic function. Edema. Hypertension. Cardiac failure. Bleeding disorders. Diabetes. Monitor blood, hepatic, renal, and ocular function in chronic use. Discontinue if visual or liver dysfunction occurs. Dehydration. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended.
Ibuprofen Pharmacokinetics
See Literature
Ibuprofen Interactions
Interactions
Avoid aspirin. May increase bleeding with anticoagulants, toxicity of methotrexate. Increases serum lithium levels. May decrease effect of furosemide, thiazide diuretics.
Ibuprofen Adverse Reactions
Adverse Reactions
Peptic ulcer or perforation, GI bleeding, vision disorders, nausea, epigastric pain, heartburn, dizziness, rash (discontinue if occurs), edema, renal papillary necrosis, jaundice, hepatitis. See literature re: risk of cardiovascular events.
Ibuprofen Clinical Trials
See Literature
Ibuprofen Note
Not Applicable
Ibuprofen Patient Counseling
See Literature
