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Hyalgan Generic Name & Formulations
Legal Class
Rx
General Description
Sodium hyaluronate 20mg/2mL; soln for intra-articular inj.
Pharmacological Class
Hyaluronan.
How Supplied
Single-use vials—1; Single-use prefilled syringes—1
Manufacturer
Generic Availability
NO
Hyalgan Indications
Indications
Treatment of pain in osteoarthritis of the knee in patients who have failed nonpharmacologic therapy and analgesics (eg, acetaminophen).
Hyalgan Dosage and Administration
Adult
Prior to treatment: remove joint effusion (use separate syringe), if present; and give local anesthetic (eg, lidocaine) by SC inj. Inject 2mL intra-articularly in each affected knee weekly for 5 weeks. Use separate vial/syringe for each knee.
Children
Not established.
Hyalgan Contraindications
Contraindications
Infection or skin disease at inj site.
Hyalgan Boxed Warnings
Not Applicable
Hyalgan Warnings/Precautions
Warnings/Precautions
Treatment cycle <3 injections: not recommended. Avian protein, feather, egg allergy. Avoid strenuous activity within 48hrs after injection. Pregnancy. Nursing mothers.
Hyalgan Pharmacokinetics
See Literature
Hyalgan Interactions
Interactions
Avoid disinfectants with quaternary ammonium salts. Concomitant other intra-articular injectables: not recommended.
Hyalgan Adverse Reactions
Adverse Reactions
Inj site pain, local reactions, transient knee inflammation.
Hyalgan Clinical Trials
See Literature
Hyalgan Note
Not Applicable
Hyalgan Patient Counseling
See Literature
