Share on Facebook
Share on Twitter
Share on LinkedIn
Share by Email
Print
Forteo Generic Name & Formulations
Legal Class
Rx
General Description
Teriparatide (recombinant) 250mcg/mL; soln for SC inj; contains m-cresol.
Pharmacological Class
Hormone (human parathyroid hormone, recombinant).
How Supplied
Prefilled pen (2.48mL)—1
Manufacturer
Forteo Indications
Indications
Postmenopausal osteoporosis in women who are at high risk for fracture. To increase bone mass in men with primary or hypogonadal osteoporosis who are at high risk for fracture. Treatment of men and women with osteoporosis associated with sustained glucocorticoid therapy at high risk for fracture (see full labeling).
Forteo Dosage and Administration
Adult
20mcg SC once daily into thigh or abdominal wall; may treat for up to 2yrs. Use for >2yrs should only be considered if a patient remains at or has returned to having a high risk for fracture.
Children
Not established.
Forteo Contraindications
Not Applicable
Forteo Boxed Warnings
Not Applicable
Forteo Warnings/Precautions
Warnings/Precautions
Increased baseline risk for osteosarcoma (eg, open epiphyses, metabolic bone disease, Paget's disease of bone, bone metastases, history of skeletal malignancies, prior skeletal radiation therapy, hereditary disorders predisposing to osteosarcoma), underlying hypercalcemia disorder (eg, primary hyperparathyroidism): avoid. Risk of cutaneous calcification including calciphylaxis in those with underlying autoimmune disease, renal failure. Discontinue if calciphylaxis or worsening of previously stable cutaneous calcification develops. Urolithiasis. Hypercalciuria. Hepatic, renal, or cardiac disease. Pregnancy. Nursing mothers: not recommended.
Forteo Pharmacokinetics
See Literature
Forteo Interactions
Interactions
Caution with digoxin (teriparatide-induced hypercalcemia increases risk of toxicity). Risk of calciphylaxis when concomitant warfarin or systemic corticosteroid.
Forteo Adverse Reactions
Adverse Reactions
Arthralgia, pain, nausea; transient orthostatic hypotension, hypercalcemia, hyperuricemia, inj site reactions.
Forteo Clinical Trials
See Literature
Forteo Note
Not Applicable
Forteo Patient Counseling
See Literature
