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Extra Strength Bayer Plus Generic Name & Formulations
Legal Class
OTC
General Description
Aspirin 500mg; buffered with calcium carbonate; caplets.
Pharmacological Class
Salicylate.
See Also
How Supplied
Ext Str tabs, caplets, Plus—50; Ext Str gelcaps—40, 80; Bayer Tabs—12, 24, 50, 100, 200, 300, 365; Caplets—50, 100, 200
Manufacturer
Extra Strength Bayer Plus Indications
Indications
Arthritic and rheumatic conditions.
Extra Strength Bayer Plus Dosage and Administration
Adult
Rheumatoid arthritis, arthritis and pleurisy of SLE: initially 3g daily in divided doses; target plasma salicylate level 150–300mcg/mL. Osteoarthritis: up to 3g/day in divided doses. Spondyloarthropathies: up to 4g/day in divided doses.
Children
JRA: initially 90–130mg/kg per day in divided doses; target plasma salicylate level 150–300mcg/mL.
Extra Strength Bayer Plus Contraindications
Contraindications
NSAID allergy. Viral infection in children and teenagers. 3rd trimester pregnancy.
Extra Strength Bayer Plus Boxed Warnings
Not Applicable
Extra Strength Bayer Plus Warnings/Precautions
Warnings/Precautions
History of asthma or peptic ulcer. Severe hepatic or renal dysfunction. Bleeding disorders. Diabetes. Gout. Pregnancy, nursing mothers: not recommended.
Extra Strength Bayer Plus Pharmacokinetics
See Literature
Extra Strength Bayer Plus Interactions
Interactions
Potentiates anticoagulants, hypoglycemics, methotrexate, acetazolamide, valproic acid, highly protein-bound drugs. Urinary alkalinizers, antacids, corticosteroids may increase excretion. May antagonize ACE inhibitors, β-blockers, diuretics, uricosurics. Increased bleeding risk with NSAIDs or chronic, heavy alcohol use. NSAIDs increase risk of renal dysfunction.
Extra Strength Bayer Plus Adverse Reactions
Adverse Reactions
GI upset/bleed, prolonged bleeding time, anaphylaxis, salicylism.
Extra Strength Bayer Plus Clinical Trials
See Literature
Extra Strength Bayer Plus Note
Not Applicable
Extra Strength Bayer Plus Patient Counseling
See Literature
Extra Strength Bayer Plus Generic Name & Formulations
Legal Class
OTC
General Description
Aspirin 500mg; buffered with calcium carbonate; caplets.
Pharmacological Class
Salicylate.
How Supplied
Tabs—12, 24, 50, 100, 200, 300, 365; Caplets—50, 100, 200; Gelcaps—40, 80; Ext Str tabs, caplets, Plus—50; Ext Str Gelcaps—40, 80; Children's—36
Manufacturer
Extra Strength Bayer Plus Indications
Indications
Pain. Fever.
Extra Strength Bayer Plus Dosage and Administration
Adult
500mg–1g every 4–6hrs; usual max 4g daily.
Children
Use chewable tabs.
Extra Strength Bayer Plus Contraindications
Contraindications
NSAID allergy. Viral infection in children and teenagers. 3rd trimester pregnancy.
Extra Strength Bayer Plus Boxed Warnings
Not Applicable
Extra Strength Bayer Plus Warnings/Precautions
Warnings/Precautions
History of asthma or peptic ulcer. Severe hepatic or renal dysfunction. Bleeding disorders. Diabetes. Gout. Pregnancy, nursing mothers: not recommended.
Extra Strength Bayer Plus Pharmacokinetics
See Literature
Extra Strength Bayer Plus Interactions
Interactions
Potentiates anticoagulants, hypoglycemics, methotrexate, acetazolamide, valproic acid, highly protein-bound drugs. Urinary alkalinizers, antacids, corticosteroids may increase excretion. May antagonize ACE inhibitors, β-blockers, diuretics, uricosurics. Increased bleeding risk with NSAIDs or chronic, heavy alcohol use. NSAIDs increase risk of renal dysfunction.
Extra Strength Bayer Plus Adverse Reactions
Adverse Reactions
GI upset/bleed, prolonged bleeding time, anaphylaxis, salicylism.
Extra Strength Bayer Plus Clinical Trials
See Literature
Extra Strength Bayer Plus Note
Not Applicable
Extra Strength Bayer Plus Patient Counseling
See Literature
