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Evista Generic Name & Formulations
Legal Class
Rx
General Description
Raloxifene HCl 60mg; tabs.
Pharmacological Class
Selective estrogen receptor modulator (SERM).
How Supplied
Tabs—30, 100, 2000
Manufacturer
Evista Indications
Indications
Prevention and treatment of osteoporosis in postmenopausal women.
Evista Dosage and Administration
Adult
60mg once daily.
Children
Not recommended.
Evista Contraindications
Contraindications
Active or history of venous thromboembolic events. Nursing mothers. Pregnancy (Cat.X). Women who may become pregnant.
Evista Boxed Warnings
Not Applicable
Evista Warnings/Precautions
Warnings/Precautions
Not for use in premenopausal women. Concomitant systemic estrogen therapy: not recommended. Discontinue 72 hours before, and during prolonged immobilization; resume when fully ambulatory. Coronary heart disease or risk of coronary event (increased risk of death due to stroke). Hepatic dysfunction. Moderate to severe renal impairment.
Evista Pharmacokinetics
See Literature
Evista Interactions
Interactions
May antagonize warfarin; monitor. Avoid concomitant cholestyramine, other anion exchange resins. Caution with other highly protein-bound drugs (eg, diazepam, diazoxide, lidocaine).
Evista Adverse Reactions
Adverse Reactions
Hot flashes, leg cramps, peripheral edema, flu syndrome, arthralgia, sweating; rare: venous thromboembolic events.
Evista Clinical Trials
See Literature
Evista Note
Not Applicable
Evista Patient Counseling
See Literature
Evista Generic Name & Formulations
Legal Class
Rx
General Description
Raloxifene HCl 60mg; tabs.
Pharmacological Class
Selective estrogen receptor modulator (SERM).
How Supplied
Tabs—30, 100, 2000
Manufacturer
Evista Indications
Indications
Reduction in risk of invasive breast cancer in postmenopausal women: with osteoporosis and/or at high risk for invasive breast cancer.
Evista Dosage and Administration
Adult
60mg once daily.
Children
Not recommended.
Evista Contraindications
Contraindications
Active or history of venous thromboembolic events. Nursing mothers. Pregnancy (Cat.X). Women who may become pregnant.
Evista Boxed Warnings
Not Applicable
Evista Warnings/Precautions
Warnings/Precautions
Not for use in premenopausal women. Concomitant systemic estrogen therapy: not recommended. Discontinue 72 hours before, and during prolonged immobilization; resume when fully ambulatory. Coronary heart disease or risk of coronary event (increased risk of death due to stroke). Hepatic dysfunction. Moderate to severe renal impairment.
Evista Pharmacokinetics
See Literature
Evista Interactions
Interactions
May antagonize warfarin; monitor. Avoid concomitant cholestyramine, other anion exchange resins. Caution with other highly protein-bound drugs (eg, diazepam, diazoxide, lidocaine).
Evista Adverse Reactions
Adverse Reactions
Hot flashes, leg cramps, peripheral edema, flu syndrome, arthralgia, sweating; rare: venous thromboembolic events.
Evista Clinical Trials
See Literature
Evista Note
Not Applicable
Evista Patient Counseling
See Literature
