Share on Facebook
Share on Twitter
Share on LinkedIn
Share by Email
Print
Amrix Generic Name & Formulations
Legal Class
Rx
General Description
Cyclobenzaprine HCl 15mg, 30mg; ext-rel caps.
Pharmacological Class
Muscle relaxant (central).
How Supplied
Caps—60
Manufacturer
Amrix Indications
Indications
Adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions.
Amrix Dosage and Administration
Adult
Swallow whole; or may sprinkle contents on applesauce and swallow immediately without chewing. Take at same time each day. 15mg once daily; may increase to 30mg/day given once daily. Max 2–3 weeks.
Children
Not established.
Amrix Contraindications
Contraindications
Acute post-MI. Arrhythmias, heart block, other conduction disturbances. CHF. Hyperthyroidism. During or within 14 days of MAOIs.
Amrix Boxed Warnings
Not Applicable
Amrix Warnings/Precautions
Warnings/Precautions
Not effective in treating spasticity associated with cerebral or spinal chord disease or in children with cerebral palsy. Consider discontinuing if significant CNS symptoms develop. Urinary retention. Angle-closure glaucoma. Increased intraocular pressure. Hepatic impairment or elderly: not recommended. Pregnancy. Nursing mothers.
Amrix Pharmacokinetics
See Literature
Amrix Interactions
Interactions
See Contraindications. Hypertensive crisis with MAOIs. Increased risk of serotonin syndrome with other serotonergic drugs (eg, SSRIs, SNRIs, tricyclic antidepressants, tramadol, bupropion, meperidine, verapamil, MAOIs); discontinue if occurs. May potentiate alcohol, barbiturates, other CNS depressants. Caution with anticholinergics. May antagonize guanethidine and similar acting compounds. May enhance seizure risk with concomitant tramadol.
Amrix Adverse Reactions
Adverse Reactions
Dry mouth, dizziness, fatigue, constipation, nausea, dyspepsia, somnolence; serotonin syndrome, cardiovascular effects.
Amrix Clinical Trials
See Literature
Amrix Note
Not Applicable
Amrix Patient Counseling
See Literature
