Carnitor Injection

— THERAPEUTIC CATEGORIES —
  • Inborn errors of metabolism

Carnitor Injection Generic Name & Formulations

General Description

Levocarnitine 1g/5mL; soln for IV bolus inj or infusion; preservative-free.

How Supplied

Tabs—90; Oral soln—118mL; Single-dose vials (5mL)—5

Carnitor Injection Indications

Indications

Secondary carnitine deficiency. Carnitine deficiency in end stage renal disease (ESRD) patients undergoing dialysis.

Carnitor Injection Dosage and Administration

Adults and Children

Secondary carnitine deficiency: 50mg/kg as slow (2–3mins) IV bolus inj or infusion; usual max 300mg/kg. May give loading dose in severe metabolic crisis: see full labeling. ESRD: initially 10–20mg/kg dry body weight as slow (2–3mins) IV bolus inj into venous return line after each dialysis session; adjust dose based on trough levocarnitine levels.

Carnitor Injection Contraindications

Not Applicable

Carnitor Injection Boxed Warnings

Not Applicable

Carnitor Injection Warnings/Precautions

Warnings/Precautions

Obtain baseline carnitine level; monitor blood chemistry, carnitine levels, vital signs, clinical condition. Seizure disorders. Renal insufficiency (oral forms). Pregnancy. Nursing mothers: not recommended.

Carnitor Injection Pharmacokinetics

See Literature

Carnitor Injection Interactions

Interactions

Monitor INR with warfarin.

Carnitor Injection Adverse Reactions

Adverse Reactions

GI upset/pain, body odor, seizures; hypersensitivity reactions (discontinue if occur). Inj: also inj site reactions.

Carnitor Injection Clinical Trials

See Literature

Carnitor Injection Note

Not Applicable

Carnitor Injection Patient Counseling

See Literature