Alli

— THERAPEUTIC CATEGORIES —
  • Obesity

Alli Generic Name & Formulations

General Description

Orlistat 60mg; caps.

Pharmacological Class

Lipase inhibitor.

How Supplied

Caps—60, 90, 120, 170

Manufacturer

Alli Indications

Indications

Adjunct to reduced-calorie, low-fat diet for weight loss in overweight adults.

Alli Dosage and Administration

Adult

≥18yrs: 1 cap with each fat-containing meal. Max: 180mg/day. Also, take a multivitamin once daily at bedtime.

Children

<18yrs: not recommended.

Alli Contraindications

Contraindications

Organ transplant. Chronic malabsorption syndrome. Cholestasis.

Alli Boxed Warnings

Not Applicable

Alli Warnings/Precautions

Warnings/Precautions

Gallbladder disorder. Pancreatitis. Kidney stones. Seizures. Pregnancy, nursing mothers: not recommended.

Alli Pharmacokinetics

See Literature

Alli Interactions

Interactions

Concomitant cyclosporine: not recommended. May decrease absorption of fat-soluble vitamins; supplement diet with a multivitamin (separate dosing by at least 2 hours). Variable effects when concomitant anticoagulants (eg, warfarin), amiodarone, antidiabetics, antiepileptics, antiretrovirals, thyroid drugs, or other weight loss products; monitor and dose adjustments may be needed.

Alli Adverse Reactions

Adverse Reactions

GI effects (oily spotting, flatus with discharge, fecal urgency, fatty/oily stools, oily evacuation, increased defecation, fecal incontinence); rare: hepatic injury.

Alli Clinical Trials

See Literature

Alli Note

Not Applicable

Alli Patient Counseling

See Literature