Vocabria

Prior to initiation, consult additional full labelings (Edurant, Cabenuva, and Apretude) to ensure appropriate therapy. Take with a meal at the same time each day. HIV-1 treatment (≥12yrs [≥35kg]): As oral lead-in: 30mg once daily in combination with Edurant (25mg/day) for approx. 1 month (≥28 days). The last oral dose should be taken on the same day Cabenuva inj is started. As oral replacement (if planned to miss a scheduled monthly Cabenuva inj by >7 days): can take daily up to 2 months to replace missed inj visits. The first oral dose should be taken 1 month (±7 days) after the last Cabenuva inj and continue until the day inj dosing is restarted; (if planned to miss a scheduled every-2-month Cabenuva inj by >7 days): can take daily up to 2 months to replace 1 missed every-2-month inj. The first oral dose should be taken approx. 2 months after the last Cabenuva inj and continue until the day inj dosing is restarted. For oral therapy with Vocabria/Edurant of durations >2 months, use alternative oral regimen. HIV-1 PrEP (≥35kg): prior to initiation, and with each subsequent Apretude inj, must have a confirmed negative HIV-1 test. As oral lead-in: 30mg once daily for approx. 1 month (≥28 days). Following oral lead-in, initiate Apretude inj on the last day of oral lead-in or within 3 days. As oral replacement (if planned to miss a scheduled Apretude inj by >7 days): can take daily to replace 1 every 2-month inj visit. The first oral dose should be taken approx. 2 months after the last Apretude inj; restart Apretude inj on the day oral dosing completes or within 3 days.