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Virazole Generic Name & Formulations
Legal Class
Rx
General Description
Ribavirin 6g/vial; pwd for reconstitution and aerosol inhalation.
Pharmacological Class
Nucleoside analogue.
How Supplied
Vials—4
Manufacturer
Virazole Indications
Indications
Severe lower respiratory infections due to respiratory syncytial virus in hospitalized infants and young children.
Virazole Dosage and Administration
Adult
Not recommended.
Children
Begin treatment preferably within first 3 days of infection. 20mg/mL as starting solution in drug reservoir for continuous aerosol administration for 12–18 hours per day for 3–7 days.
Virazole Contraindications
Contraindications
Pregnancy (Cat.X).
Virazole Boxed Warnings
Boxed Warning
Should be undertaken only by experienced physicians and support staff. Sudden deterioration of respiratory function in infants. Not indicated for use in adults.
Virazole Warnings/Precautions
Warnings/Precautions
See full labeling. Monitor respiratory function, fluid status. Discontinue if sudden deterioration of respiratory function. Use with mechanical ventilators should be undertaken only by physicians and support staff familiar with this mode of administration. Drug may precipitate in mechanical ventilator, causing dysfunction. Avoid unnecessary occupational exposure. Nursing mothers.
Virazole Pharmacokinetics
See Literature
Virazole Interactions
Interactions
Monitor digitalis.
Virazole Adverse Reactions
Adverse Reactions
Pulmonary function deterioration, bronchospasm, pulmonary edema, hypoventilation, bacterial pneumonia, pneumothorax, apnea, ventilator dependence, atelectasis, cardiac arrest, hypotension, reticulocytosis, hemolytic anemia, rash, conjunctivitis.
Virazole Clinical Trials
See Literature
Virazole Note
Not Applicable
Virazole Patient Counseling
See Literature
