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Sivextro Generic Name & Formulations
Legal Class
Rx
General Description
Tedizolid phosphate 200mg; tabs.
Pharmacological Class
Oxazolidinone.
See Also
How Supplied
Tabs—6 (blister pack), 30; Single-dose vials—10
Manufacturer
Generic Availability
NO
Sivextro Indications
Indications
Susceptible acute bacterial skin and skin structure infections (ABSSSI).
Sivextro Dosage and Administration
Adults and Children
<12yrs: not established. ≥12yrs: 200mg once daily for 6 days.
Sivextro Contraindications
Not Applicable
Sivextro Boxed Warnings
Not Applicable
Sivextro Warnings/Precautions
Warnings/Precautions
Not adequately evaluated in patients with neutropenia (ANC <1000 cells/mm3); consider alternate therapies. Risk of C. difficile-associated diarrhea; discontinue if suspected or confirmed. Pregnancy. Nursing mothers.
Sivextro Pharmacokinetics
See Literature
Sivextro Interactions
Interactions
Tabs: May potentiate oral BCRP substrates; consider interrupting co-administered substrates esp. those with narrow therapeutic index (eg, methotrexate, topotecan); monitor if coadministration (including rosuvastatin) is necessary.
Sivextro Adverse Reactions
Adverse Reactions
Nausea, headache, diarrhea, infusion- or inj site reactions, vomiting, dizziness. In children: phlebitis, increased hepatic transaminases.
Sivextro Clinical Trials
See Literature
Sivextro Note
Not Applicable
Sivextro Patient Counseling
See Literature
