Share on Facebook
Share on Twitter
Share on LinkedIn
Share by Email
Print
Relenza Generic Name & Formulations
Legal Class
Rx
General Description
Zanamivir 5mg/blister; dry pwd for oral inhalation; contains lactose.
Pharmacological Class
Neuraminidase inhibitor.
How Supplied
Rotadisk (4 blisters)—5 (w. 1 Diskhaler)
Manufacturer
Relenza Indications
Indications
Treatment of uncomplicated acute illness due to influenza A and B virus in patients ≥7 years of age who have been symptomatic for no more than two days. Prophylaxis of influenza in patients ≥5 years of age.
Relenza Dosage and Administration
Adults and Children
Use supplied Diskhaler inhalation device. Complete course of treatment. Treatment: <7yrs: not established. ≥7yrs: 2 inh (10mg total) twice daily (at least 2 hrs apart) on 1st day; then 2 inh (10mg total) twice daily at 12-hr intervals for the next 4 days (5 days total). Prophylaxis: <5yrs: not established. ≥5yrs: 2 inh (10mg total) once daily. Household: use for 10 days. Community: use for 28 days.
Relenza Contraindications
Contraindications
Milk protein allergy.
Relenza Boxed Warnings
Not Applicable
Relenza Warnings/Precautions
Warnings/Precautions
Underlying airway disease (eg, asthma, COPD): not recommended; if used, patient must have a fast-acting bronchodilator available. Discontinue if bronchospasm or decline in respiratory function occurs or worsens. Do not use for prophylaxis in nursing home setting. Monitor for signs of abnormal behavior (esp. in children). High-risk underlying medical conditions. Pregnancy. Nursing mothers.
Relenza Pharmacokinetics
See Literature
Relenza Interactions
Interactions
If an inhaled bronchodilator is scheduled for dosing at the same time, use the bronchodilator first. Caution with influenza virus vaccine live, intranasal (eg, FluMist); separate dosing by at least 48hrs before or 2 weeks after FluMist. May maintain normal influenza virus vaccine schedule.
Relenza Adverse Reactions
Adverse Reactions
Sinusitis, dizziness, fever/chills, arthralgia, articular rheumatism; bronchospasm, allergic reactions (eg, oropharyngeal edema), possible neuropsychiatric events (eg, seizures, confusion, abnormal behavior).
Relenza Clinical Trials
See Literature
Relenza Note
Not Applicable
Relenza Patient Counseling
See Literature
Images
