Impavido

Embryo-fetal toxicity; obtain a serum or urine pregnancy test in females of reproductive potential prior to prescribing; use effective contraception during therapy and for 5 months after completion; use additional non-hormonal or alternative methods of contraception if vomiting/diarrhea occur during therapy. Possibly reproductive effects (eg, impaired fertility). Monitor renal function weekly during therapy and for 4 weeks after completion. Monitor platelets (for visceral leishmaniasis), ALT, AST, and bilirubin during therapy. Maintain adequate hydration. Discontinue if exfoliative or bullous rash develops. Nursing mothers: not recommended (during and for 5 months after therapy).