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Gris-peg Generic Name & Formulations
Legal Class
Rx
General Description
Griseofulvin 125mg, 250mg; ultramicrosize; scored tabs.
How Supplied
Tabs 125mg—100; 250mg—100, 500
Manufacturer
Gris-peg Indications
Indications
Ringworm infections of the skin, scalp, and nails.
Gris-peg Dosage and Administration
Adult
375mg daily as 1 or more divided doses; max 750mg daily.
Children
<2 yrs: not recommended. 35-60lbs: 125–187.5mg daily. >60lbs: 187.5mg–375mg daily.
Gris-peg Contraindications
Contraindications
Porphyria. Hepatocellular failure. Pregnancy.
Gris-peg Boxed Warnings
Not Applicable
Gris-peg Warnings/Precautions
Warnings/Precautions
Continue therapy until infection is eradicated. Periodic monitoring of renal, hepatic, and hematopoietic functions. Discontinue if granulocytopenia occurs. Penicillin sensitivity. Avoid exposure to sunlight or UV light. Nursing mothers.
Gris-peg Pharmacokinetics
See Literature
Gris-peg Interactions
Interactions
Antagonizes oral anticoagulants. Antagonized by barbiturates. May potentiate alcohol. Oral contraceptives may be less effective.
Gris-peg Adverse Reactions
Adverse Reactions
Oral thrush, GI distress, dizziness, confusion, peripheral neuritis, photosensitivity, granulocytopenia, leukopenia, proteinuria, lupus-like syndrome.
Gris-peg Clinical Trials
See Literature
Gris-peg Note
Not Applicable
Gris-peg Patient Counseling
See Literature
