EMTRIVA ORAL SOLUTION Dosage & Rx Info

Emtriva Oral Solution Generic Name & Formulations

Legal Class

General Description

Emtricitabine 10mg/mL; cotton candy flavor.

Pharmacological Class

Nucleoside analogue (reverse transcriptase inhibitor).

How Supplied

Caps—30; Soln—170mL

Manufacturer

Gilead Sciences, Inc.

Emtriva Oral Solution Indications

Indications

HIV-1 infection, in combination with other antiretroviral agents.

Emtriva Oral Solution Dosage and Administration

Adult

≥18yrs: 240mg (24mL) once daily. Renal impairment: (CrCl 30–49mL/min): 120mg (12mL) once daily; (CrCl 15–29mL/min): 80mg (8mL) once daily; (CrCl <15mL/min or dialysis): 60mg (6mL) once daily.

Children

<3mos: 3mg/kg once daily. 3mos–17yrs: 6mg/kg [max 240mg (24mL)] once daily. >33kg: may use cap form. Renal impairment: reduce dose or prolong dosing interval (see full labeling).

Emtriva Oral Solution Contraindications

Not Applicable

Emtriva Oral Solution Boxed Warnings

Boxed Warning

Posttreatment exacerbation of hepatitis B.

Emtriva Oral Solution Warnings/Precautions

Warnings/Precautions

Not for treating chronic HBV infection; test for HBV before starting therapy and closely monitor patients co-infected with HBV and HIV for several months after stopping treatment (discontinuing therapy may exacerbate HBV infection); if appropriate, initiate anti-hepatitis B therapy may be warranted. Suspend therapy if lactic acidosis or hepatotoxicity (eg, hepatomegaly, steatosis) occurs. Renal impairment. Pregnancy (Cat.B). Nursing mothers: not recommended.

Emtriva Oral Solution Pharmacokinetics

See Literature

Emtriva Oral Solution Interactions

Interactions

Avoid concomitant drugs that contain emtricitabine or lamivudine (eg, fixed dose combination products).

Emtriva Oral Solution Adverse Reactions

Adverse Reactions

Headache, diarrhea, nausea, fatigue, dizziness, depression, insomnia, abnormal dreams, rash, abdominal pain, asthenia, increased cough, rhinitis; new onset or worsening renal impairment, immune reconstitution syndrome; also children: skin hyperpigmentation.

Emtriva Oral Solution

PAGE CONTENTS