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Cefuroxime Generic Name & Formulations
Legal Class
Rx
General Description
Cefuroxime (as axetil) 250mg, 500mg; tabs.
Pharmacological Class
Cephalosporin.
How Supplied
Contact supplier
Manufacturer
Cefuroxime Indications
Indications
Susceptible mild to moderate infections including pharyngitis/tonsillitis, acute maxillary sinusitis, chronic bronchitis, acute otitis media, uncomplicated skin and skin structure, UTIs, gonorrhea, early Lyme disease.
Cefuroxime Dosage and Administration
Adult
Swallow whole. ≥13yrs: Pharyngitis/tonsillitis, sinusitis: 250mg twice daily for 10 days. Acute bacterial exacerbations of chronic bronchitis, skin and skin structure infections: 250–500mg twice daily for 10 days. UTIs: 250mg twice daily for 7–10 days. Gonorrhea: 1g as a single dose. Lyme disease: 500mg twice daily for 20 days. Renal impairment: see full labeling.
Children
Swallow whole. <13yrs (able to swallow tab): Otitis media, sinusitis: 250mg twice daily for 10 days.
Cefuroxime Contraindications
Contraindications
β-lactam allergy.
Cefuroxime Boxed Warnings
Not Applicable
Cefuroxime Warnings/Precautions
Warnings/Precautions
Renal impairment. Elderly. Pregnancy. Nursing mothers.
Cefuroxime Pharmacokinetics
See Literature
Cefuroxime Interactions
Interactions
Potentiated by probenecid; not recommended. May antagonize oral contraceptives; consider non-hormonal methods. Avoid H2-blockers, PPIs. Separate cefuroxime by ≥1hr before or 2hrs after antacids. May interfere with glucose tests.
Cefuroxime Adverse Reactions
Adverse Reactions
Diarrhea, nausea, vomiting, Jarisch-Herxheimer reaction, vaginitis; anaphylactic reactions (discontinue if occur), C. difficile-associated diarrhea.
Cefuroxime Clinical Trials
See Literature
Cefuroxime Note
Notes
Formerly known under the brand name Ceftin.
Cefuroxime Patient Counseling
See Literature
