Cefpodoxime Proxetil Generic Name & Formulations
Legal Class
Rx
General Description
Cefpodoxime proxetil 100mg, 200mg; tabs.
Pharmacological Class
Cephalosporin.
How Supplied
Contact supplier.
Manufacturer
Cefpodoxime Proxetil Indications
Indications
Susceptible mild to moderate infections including acute otitis media, acute bacterial exacerbations of chronic bronchitis, acute maxillary sinusitis, pharyngitis/tonsillitis, acute community-acquired pneumonia, urinary tract, skin and skin structures; cervical, anorectal (females only) and urethral gonorrhea.
Cefpodoxime Proxetil Dosage and Administration
Adult
Take tabs with food. ≥13yrs: Pneumonia: 200mg every 12hrs for 14 days. Bronchitis, sinusitis: 200mg every 12hrs for 10 days. Pharyngitis/tonsillitis: 100mg every 12hrs for 5–10 days. Skin and skin structures: 400mg every 12hrs for 7–14 days. UTI: 100mg every 12hrs for 7 days. Uncomplicated gonorrhea: 200mg once as a single dose. Renal failure or hemodialysis: see full labeling.
Children
Use susp. <2 months: not recommended. 2 months–12yrs: Acute otitis media: 5mg/kg (max 200mg) every 12hrs for 5 days. Pharyngitis/tonsillitis: 5mg/kg (max 100mg) every 12hrs for 5–10 days. Sinusitis: 5mg/kg (max 200mg) every 12hrs for 10 days.
Cefpodoxime Proxetil Contraindications
Not Applicable
Cefpodoxime Proxetil Boxed Warnings
Not Applicable
Cefpodoxime Proxetil Warnings/Precautions
Warnings/Precautions
Penicillin or other allergy. Labor & delivery. Pregnancy (Cat.B). Nursing mothers: not recommended.
Cefpodoxime Proxetil Pharmacokinetics
See Literature
Cefpodoxime Proxetil Interactions
Interactions
Antacids, H2 antagonists, oral anticholinergics may decrease efficacy. Potentiated by probenecid. Avoid concomitant diuretics, other nephrotoxic drugs. May cause false (+) direct Coomb's test.
Cefpodoxime Proxetil Adverse Reactions
Adverse Reactions
GI upset, abdominal pain, headache, rash, anaphylaxis.
Cefpodoxime Proxetil Clinical Trials
See Literature
Cefpodoxime Proxetil Note
Notes
Formerly known under the brand name Vantin.
Cefpodoxime Proxetil Patient Counseling
See Literature