Share on Facebook
Share on Twitter
Share on LinkedIn
Share by Email
Print
Cefoxitin Injection Generic Name & Formulations
Legal Class
Rx
General Description
Cefoxitin sodium 1g, 2g; for IV inj; sodium content 2.3mEq/g.
Pharmacological Class
Cephalosporin.
How Supplied
Contact supplier.
Manufacturer
Cefoxitin Injection Indications
Indications
Susceptible bacterial septicemia, lower respiratory or urinary tract, skin and skin structure, bone and joint, gynecologic, intraabdominal infections. Surgical prophylaxis.
Cefoxitin Injection Dosage and Administration
Adult
Usually 1–2g every 6–8hrs. Uncomplicated: 1g every 6–8hrs. Moderately severe to severe: 1g every 4hrs or 2g every 6–8hrs. Max 2g every 4hrs or 3g every 6hrs. Prophylaxis: see literature.
Children
<3months: not recommended. ≥3months: 80–160mg/kg per day in 4–6 equal divided doses; max 12g/day. Prophylaxis: see literature.
Cefoxitin Injection Contraindications
Not Applicable
Cefoxitin Injection Boxed Warnings
Not Applicable
Cefoxitin Injection Warnings/Precautions
Warnings/Precautions
Penicillin or other allergy. Renal impairment (CrCl <50mL/min), reduce dose: see literature. GI disease (esp. colitis). Pregnancy (Cat.B). Nursing mothers.
Cefoxitin Injection Pharmacokinetics
See Literature
Cefoxitin Injection Interactions
Interactions
Aminoglycosides may potentiate nephrotoxicity. Potentiated by probenecid. May cause false (+) Clinitest. May interfere with creatinine tests.
Cefoxitin Injection Adverse Reactions
Adverse Reactions
Local reactions, rash, pruritus, drug fever, GI upset, anaphylaxis, blood dyscrasias, elevated liver enzymes.
Cefoxitin Injection Clinical Trials
See Literature
Cefoxitin Injection Note
Notes
Formerly known under the brand name Mefoxin.
Cefoxitin Injection Patient Counseling
See Literature
