Cefaclor

— THERAPEUTIC CATEGORIES —
  • Bacterial infections

Cefaclor Generic Name & Formulations

General Description

Cefaclor 250mg, 500mg; caps.

Pharmacological Class

Cephalosporin.

How Supplied

Contact supplier.

Cefaclor Indications

Indications

Susceptible infections including otitis media, lower respiratory or urinary tract, pharyngitis/tonsillitis, skin and skin structure.

Cefaclor Dosage and Administration

Adult

250–500mg every 8 hrs.

Children

<1month: not recommended. ≥1month: 20mg/kg per day in 3 equally divided doses. Otitis media, more serious or less susceptible infections: 40mg/kg per day in 3 equally divided doses (may give in 2 divided doses for pharyngitis or otitis media); max 1g/day.

Cefaclor Contraindications

Not Applicable

Cefaclor Boxed Warnings

Not Applicable

Cefaclor Warnings/Precautions

Warnings/Precautions

Penicillin or other allergy. Discontinue if colitis occurs and treat. Severe renal dysfunction. GI disease (esp. colitis). Pregnancy (Cat.B). Nursing mothers.

Cefaclor Pharmacokinetics

See Literature

Cefaclor Interactions

Interactions

May cause false (+) Coomb's test or glucose test with Clinitest or Benedict's or Fehling's soln. Potentiated by probenecid. Monitor warfarin. ER: antagonized by concomitant (within 1 hr) aluminum or magnesium-containing antacids.

Cefaclor Adverse Reactions

Adverse Reactions

Headache, GI upset, rash, blood dyscrasias, hepatic dysfunction, cough, CNS stimulation, serum-sickness-like reactions.

Cefaclor Clinical Trials

See Literature

Cefaclor Note

Notes

Formerly known under the brand names Ceclor CD (ext-rel tabs); Ceclor (caps, susp); Raniclor (caps).

Cefaclor Patient Counseling

See Literature