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Cayston Generic Name & Formulations
Legal Class
Rx
General Description
Aztreonam 75mg/vial; pwd for inhalation via nebulization after reconstitution; preservative-free.
Pharmacological Class
Monobactam.
How Supplied
Vials—84 (w. diluent)
Manufacturer
Generic Availability
NO
Cayston Indications
Indications
To improve respiratory symptoms in cystic fibrosis patients with Pseudomonas aeruginosa.
Cayston Dosage and Administration
Adults and Children
<7yrs: not established. Use a short-acting bronchodilator 15 minutes to 4 hours before each dose; or a long-acting bronchodilator 30 minutes to 12 hours before starting therapy. >7yrs: 75mg (1 vial) by nebulization three times daily (at least 4 hours apart) for 28 days. Use Altera Nebulizer only.
Cayston Contraindications
Not Applicable
Cayston Boxed Warnings
Not Applicable
Cayston Warnings/Precautions
Warnings/Precautions
Monobactam or beta-lactam allergy. FEV<25% or >75% predicted, patients colonized with Burkholderia cepacia: safety/effectiveness not established. Pregnancy. Nursing mothers.
Cayston Pharmacokinetics
See Literature
Cayston Interactions
Interactions
Do not mix with other drugs in nebulizer.
Cayston Adverse Reactions
Adverse Reactions
Cough, nasal congestion, wheezing, pharyngolaryngeal pain, pyrexia, chest discomfort, abdominal pain, vomiting, rash; chest tightness, bronchospasm, allergic reactions (discontinue if occurs).
Cayston Clinical Trials
See Literature
Cayston Note
Notes
To support and assist patients with cystic fibrosis contact the Cayston Access Program at (877) 7CAYSTON. Should be administered immediately after reconstitution. Do not reconstitute until ready to administer a dose.
Cayston Patient Counseling
See Literature
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