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Ampicillin Generic Name & Formulations
Legal Class
Rx
General Description
Ampicillin 250mg, 500mg; caps.
Pharmacological Class
Broad-spectrum penicillin.
See Also
How Supplied
Contact supplier.
Manufacturer
Mechanism of Action
Ampicillin is similar to penicillin in its bactericidal action against susceptible bacteria during the stage of active multiplication. It acts through the inhibition of cell wall biosynthesis that leads to the death of the bacteria.
Ampicillin Indications
Indications
Ampicillin-sensitive infections.
Ampicillin Dosage and Administration
Adult
250–500mg 4 times daily. Continue therapy for 3 days after symptoms improve. N. gonorrhoeae: 3.5g with 1g probenecid once.
Children
<20kg: 50–100mg/kg per day in 3–4 divided doses. ≥20kg: as adult. Continue therapy for 3 days after symptoms improve.
Ampicillin Contraindications
Not Applicable
Ampicillin Boxed Warnings
Not Applicable
Ampicillin Warnings/Precautions
Warnings/Precautions
Cephalosporin, imipenem, other allergy or mononucleosis: not recommended. Monitor blood, renal, and liver function in long-term use. Pregnancy (Cat.B). Nursing mothers.
Ampicillin Pharmacokinetics
Elimination
Renal.
Ampicillin Interactions
Interactions
May cause false (+) glucose test with Clinitest, Benedict's or Fehling's soln. Potentiated by probenecid. May increase risk of rash with allopurinol.
Ampicillin Adverse Reactions
Adverse Reactions
Anaphylaxis, urticaria, GI upset, blood dyscrasias.
Ampicillin Clinical Trials
See Literature
Ampicillin Note
Notes
Formerly known under the brand names Principen, Totacillin, Pfizerpen-A, Penbritin, Omnipen, Amcill (caps, susp); Polycillin-N, Totacillin-N, Penbritin-S, Omnipen-N (inj).
Ampicillin Patient Counseling
See Literature
