Amoxicillin Tablets Dosage & Rx Info

Amoxicillin Tablets Generic Name & Formulations

Legal Class

General Description

Amoxicillin (as trihydrate) 500mg, 875mg; tabs.

Pharmacological Class

Broad-spectrum penicillin.

How Supplied

Contact supplier

Manufacturer

Various generic manufacturers

Amoxicillin Tablets Indications

Indications

Susceptible infections including ear/nose/throat (ENT), genitourinary tract, skin and skin structures, lower respiratory, acute uncomplicated gonorrhea.

Amoxicillin Tablets Dosage and Administration

Adult

>40kg: ENT: mild/moderate: 500mg every 12hrs; severe: 875mg every 12hrs. Lower respiratory tract: 875mg every 12hrs. Skin/skin structure: mild/moderate: 500mg every 12hrs; severe: 875mg every 12hrs. Genitourinary tract: mild/moderate: 500mg every 12hrs; severe: 875mg every 12hrs. Gonorrhea, acute uncomplicated ano-genital and urethral infections: 3g as single oral dose.

Children

≤3 months: max 30mg/kg per day in 2 divided doses every 12hrs. >3 months (<40kg): ENT, genitourinary, skin: 25mg/kg/day in divided doses every 12hrs. Severe infections, or lower respiratory infections: 45mg/kg/day in divided doses every 12hrs. Gonorrhea: <2yrs: not recommended; prepubertal: amoxicillin 50mg/kg + probenecid 25mg/kg as a single dose.

Amoxicillin Tablets Contraindications

Not Applicable

Amoxicillin Tablets Boxed Warnings

Not Applicable

Amoxicillin Tablets Warnings/Precautions

Warnings/Precautions

Cephalosporin, imipenem or other allergy: not recommended. Monitor blood, renal, and hepatic function in long-term use. Monitor closely if skin rash develops; discontinue if lesions progress. Mononucleosis. Labor & delivery. Pregnancy (Cat.B). Nursing mothers.

Amoxicillin Tablets Pharmacokinetics

Metabolism

Hepatic.

Elimination

Renal. Half-life: 61.3 minutes.

Amoxicillin Tablets Interactions

Interactions

May cause false (+) glucose test with Clinitest, Benedict's or Fehling's soln. Serum levels increased by probenecid.

Amoxicillin Tablets Adverse Reactions

Adverse Reactions

Diarrhea, rash, vomiting, nausea; anaphylaxis, severe cutaneous adverse reactions (eg, SJS, TEN, DRESS, AGEP), hyperactivity, blood dyscrasias.

Amoxicillin Tablets Clinical Trials

See Literature

Amoxicillin Tablets Note

Notes

Formerly known under the brand names Amoxil, Trimox, Ultimox, Wymox (caps, susp), Polymox (susp).

Amoxicillin Tablets Patient Counseling