Firdapse

<6yrs: not established. ≥6yrs (<45kg): Initially 5–15mg daily in 3–4 divided doses; may increase by 2.5mg every 3 or 4 days (max single dose: 10mg; max total: 40mg/day). ≥6yrs (≥45kg): Initially 15–30mg daily in 3–4 divided doses; may increase by 5mg every 3 or 4 days (max single dose: 20mg; max total: 80mg/day). Hepatic or renal impairment (CrCl 15–90mL/min), NAT2 poor metabolizers: 15mg daily (for patients ≥45kg) and 5mg daily (for patients <45kg) in 3 divided doses. Patients who require dosage <5mg increments, have difficulty swallowing, or require feeding tubes: may prepare a 1mg/mL oral suspension; see full labeling.