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Sajazir Generic Name & Formulations
Legal Class
Rx
General Description
Icatibant 10mg/mL; soln for SC inj; preservative-free.
Pharmacological Class
Bradykinin B2 receptor antagonist.
How Supplied
Single-dose prefilled syringe (3mL)—1, 3
Manufacturer
Generic Availability
NO
Sajazir Indications
Indications
For acute attacks of hereditary angioedema (HAE).
Sajazir Dosage and Administration
Adult
≥18yrs: 30mg SC in abdominal area; may give additional doses at intervals of at least 6hrs if response is inadequate or symptoms recur. Max 3 doses/24hrs.
Children
<18yrs: not established.
Sajazir Contraindications
Not Applicable
Sajazir Boxed Warnings
Not Applicable
Sajazir Warnings/Precautions
Warnings/Precautions
Advise patients to seek medical attention after treating laryngeal attack given the potential for airway obstruction. Elderly. Pregnancy. Nursing mothers.
Sajazir Pharmacokinetics
Elimination
Renal.
Sajazir Interactions
Interactions
May attenuate the antihypertensive effect of ACE inhibitors.
Sajazir Adverse Reactions
Adverse Reactions
Inj site reactions, pyrexia, transaminase increase, dizziness, rash.
Sajazir Clinical Trials
See Literature
Sajazir Note
Not Applicable
Sajazir Patient Counseling
See Literature
