Nimodipine Capsules Generic Name & Formulations
Legal Class
Rx
General Description
Nimodipine 30mg; soft-gel caps.
Pharmacological Class
Calcium channel blocker (CCB).
How Supplied
Contact supplier.
Manufacturer
Nimodipine Capsules Indications
Indications
To improve neurological outcome of subarachnoid hemorrhage from ruptured intracranial berry aneurysms, regardless of post-ictus neurological condition.
Nimodipine Capsules Dosage and Administration
Adult
Take on empty stomach. 60mg every 4 hours for 21 consecutive days. Start within 96 hours of subarachnoid hemorrhage. If oral therapy is not feasible, may extract capsule contents into a syringe and give via in situ NG tube, then flush tube with normal saline. Hepatic impairment: 30mg every 4 hours; monitor.
Children
Not recommended.
Nimodipine Capsules Contraindications
Not Applicable
Nimodipine Capsules Boxed Warnings
Not Applicable
Nimodipine Capsules Warnings/Precautions
Warnings/Precautions
Not for IV or other parenteral administration (may be fatal). Hepatic impairment. Monitor BP, heart rate. Pregnancy (Cat.C). Nursing mothers: not recommended.
Nimodipine Capsules Pharmacokinetics
See Literature
Nimodipine Capsules Interactions
Interactions
May potentiate other calcium channel blockers. Potentiated by cimetidine.
Nimodipine Capsules Adverse Reactions
Adverse Reactions
Decreased blood pressure, GI upset, headache, bradycardia, flushing, edema, rash; rare: intestinal pseudo-obstruction and ileus.
Nimodipine Capsules Clinical Trials
See Literature
Nimodipine Capsules Note
Notes
Formerly known under the brand name Nimotop.
Nimodipine Capsules Patient Counseling
See Literature