Nimodipine Capsules

— THERAPEUTIC CATEGORIES —
  • Miscellaneous hematological agents

Nimodipine Capsules Generic Name & Formulations

General Description

Nimodipine 30mg; soft-gel caps.

Pharmacological Class

Calcium channel blocker (CCB).

How Supplied

Contact supplier.

Nimodipine Capsules Indications

Indications

To improve neurological outcome of subarachnoid hemorrhage from ruptured intracranial berry aneurysms, regardless of post-ictus neurological condition.

Nimodipine Capsules Dosage and Administration

Adult

Take on empty stomach. 60mg every 4 hours for 21 consecutive days. Start within 96 hours of subarachnoid hemorrhage. If oral therapy is not feasible, may extract capsule contents into a syringe and give via in situ NG tube, then flush tube with normal saline. Hepatic impairment: 30mg every 4 hours; monitor.

Children

Not recommended.

Nimodipine Capsules Contraindications

Not Applicable

Nimodipine Capsules Boxed Warnings

Not Applicable

Nimodipine Capsules Warnings/Precautions

Warnings/Precautions

Not for IV or other parenteral administration (may be fatal). Hepatic impairment. Monitor BP, heart rate. Pregnancy (Cat.C). Nursing mothers: not recommended.

Nimodipine Capsules Pharmacokinetics

See Literature

Nimodipine Capsules Interactions

Interactions

May potentiate other calcium channel blockers. Potentiated by cimetidine.

Nimodipine Capsules Adverse Reactions

Adverse Reactions

Decreased blood pressure, GI upset, headache, bradycardia, flushing, edema, rash; rare: intestinal pseudo-obstruction and ileus.

Nimodipine Capsules Clinical Trials

See Literature

Nimodipine Capsules Note

Notes

Formerly known under the brand name Nimotop.

Nimodipine Capsules Patient Counseling

See Literature